Fasenra and Hydrochlorothiazide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fasenra (benralizumab) and Hydrochlorothiazide (hydrochlorothiazide). Common drug interactions include depression among females and asthma among males.

The phase IV clinical study analyzes what interactions people have when they take Fasenra and Hydrochlorothiazide. It is created by eHealthMe based on reports of 60 people who take the same drugs from the FDA, and is updated regularly.

What is Fasenra?

Fasenra has active ingredients of benralizumab. eHealthMe is studying from 11,805 Fasenra users. Check the latest studies of Fasenra.

What is Hydrochlorothiazide?

Hydrochlorothiazide has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 182,195 Hydrochlorothiazide users. Check the latest studies of Hydrochlorothiazide.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 02, 2026

60 people who take Fasenra and Hydrochlorothiazide together, and have interactions are studied.

Fasenra and Hydrochlorothiazide drug interactions.

What are the common drug interactions of Fasenra and Hydrochlorothiazide, by gender? *:

female:

  1. Depression
  2. Normal tension glaucoma (a unique condition in which optic nerve damage and vision loss have occurred despite a normal pressure inside the eye)
  3. Abdominal discomfort
  4. Anaphylactic reaction (serious allergic reaction)
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  6. Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
  7. Cardiomegaly (increased size of heart than normal)
  8. Cellulitis (infection under the skin)
  9. Chest discomfort
  10. Cholecystitis (infection of gallbladder)

male:

  1. Asthma
  2. Drug ineffective
  3. Hydrocele
  4. Nephrolithiasis (calculi in the kidneys)
  5. Pericardial effusion (fluid around the heart)
  6. Peripheral swelling
  7. Pleural effusion (water on the lungs)
  8. Prostatomegaly (enlargement of the prostate)
  9. Renal cyst (kidney cyst)
  10. Diarrhoea

What are the common drug interactions of Fasenra and Hydrochlorothiazide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Cystic fibrosis (disease of the secretary glands)

30-39:

  1. Hospitalisation
  2. Respiratory syncytial virus infection (viral disease of respiratory system)

40-49:

  1. Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
  2. Anaphylactic reaction (serious allergic reaction)
  3. Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
  4. Hospitalisation
  5. Respiratory failure (inadequate gas exchange by the respiratory system)

50-59:

  1. Essential hypertension (primary hypertension)
  2. Hyperhidrosis (abnormally increased sweating)
  3. Hypersensitivity
  4. Hypotension (abnormally low blood pressure)
  5. Ill-defined disorder
  6. Influenza
  7. Nasopharyngitis (inflammation of the nasopharynx)
  8. Pneumonia
  9. Pyrexia (fever)
  10. Respiratory distress (difficulty in breathing)

60+:

  1. Cough
  2. Dyspnoea (difficult or laboured respiration)
  3. Atelectasis (partial or complete collapse of the lung)
  4. Benign prostatic hyperplasia (benign enlargement of the prostate)
  5. Bladder hypertrophy (bladder overgrowth- increase in cell size)
  6. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  7. Gastroduodenitis (an inflammation of the mucous membrane of the stomach and duodenum)
  8. General physical health deterioration (weak health status)
  9. Hepatic cyst
  10. Hydrocele

What are the existing conditions these people have? *

  1. Asthma: 46 people, 76.67%
  2. Immunodeficiency Common Variable: 6 people, 10.00%
  3. Cough: 3 people, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Fasenra and Hydrochlorothiazide?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Fasenra and Hydrochlorothiazide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Fasenra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Hydrochlorothiazide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Fasenra and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hydrochlorothiazide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on benralizumab and hydrochlorothiazide (the active ingredients of Fasenra and Hydrochlorothiazide, respectively), and Fasenra and Hydrochlorothiazide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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