Felodipine and Naprosyn drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Felodipine (felodipine) and Naprosyn (naproxen). Common drug interactions include migraine among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Felodipine and Naprosyn. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Felodipine?

Felodipine has active ingredients of felodipine. It is often used in high blood pressure. eHealthMe is studying from 15,120 Felodipine users. Check the latest studies of Felodipine.

What is Naprosyn?

Naprosyn has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 16,738 Naprosyn users. Check the latest studies of Naprosyn.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

20 people who take Felodipine and Naprosyn together, and have interactions are studied.

Felodipine and Naprosyn drug interactions.

What are the common drug interactions of Felodipine and Naprosyn, by gender? *:

female:

Migraine (headache)
Muscle twitching
Muscular weakness (muscle weakness)
Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pain in extremity
Pain of skin
Palpitations (feelings or sensations that your heart is pounding or racing)

male:

Arthralgia (joint pain)
Chronic kidney disease
Influenza like illness
Injection site haemorrhage (bleeding from injection site)
Pain in extremity
Pruritus (severe itching of the skin)
Renal failure acute (rapid kidney dysfunction)
Sluggishness (lacking alertness)
Somnolence (a state of near-sleep, a strong desire for sleep)
Temperature intolerance (inability to go in temperature)

What are the common drug interactions of Felodipine and Naprosyn, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Chronic kidney disease
Renal failure (kidney dysfunction)
Nephropathy (damage to or disease of a kidney)

40-49:

Adverse event
Cardiac failure congestive
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic foot
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Erectile dysfunction
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Neuropathy peripheral (surface nerve damage)
Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously)

50-59:

Arthralgia (joint pain)
Cataract (clouding of the lens inside the eye)
Hyperhidrosis (abnormally increased sweating)
Influenza like illness
Temperature intolerance (inability to go in temperature)
Dyspepsia (indigestion)
Nosocomial infection (infection from hospital)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Postoperative fever
Pruritus (severe itching of the skin)

60+:

Pain in extremity
Accidental needle stick
Somnolence (a state of near-sleep, a strong desire for sleep)
Abasia (inability to walk)
Application site pain
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood creatinine increased
Constipation
Diarrhoea
Drug hypersensitivity

What are the existing conditions these people have? *

Muscle Spasms (muscle contraction): 3 people, 15.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 15.00%
Joint Pain: 2 people, 10.00%
Dizziness: 2 people, 10.00%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 10.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 10.00%
Gout (uric acid crystals building up in the body): 2 people, 10.00%
Haemorrhoids (a swollen vein or group of veins in the region of the anus): 2 people, 10.00%
High Blood Cholesterol: 2 people, 10.00%
Insomnia (sleeplessness): 2 people, 10.00%

* Approximation only. Some reports may have incomplete information.

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