Felodipine and Rapamune drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Felodipine (felodipine) and Rapamune (sirolimus). Common drug interactions include anaphylactic reaction among females and abdominal distension among males.

The phase IV clinical study analyzes what interactions people have when they take Felodipine and Rapamune. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Felodipine?

Felodipine has active ingredients of felodipine. It is often used in high blood pressure. eHealthMe is studying from 15,120 Felodipine users. Check the latest studies of Felodipine.

What is Rapamune?

Rapamune has active ingredients of sirolimus. It is often used in kidney transplant. eHealthMe is studying from 13,848 Rapamune users. Check the latest studies of Rapamune.

On Jul, 17, 2026

21 people who take Felodipine and Rapamune together, and have interactions are studied.

Felodipine and Rapamune drug interactions.

What are the common drug interactions of Felodipine and Rapamune, by gender? *:

female:

Anaphylactic reaction (serious allergic reaction)
Aneurysm ruptured (expansion of the aneurysm reaches a point where the wall becomes too thin, the aneurysm will rupture)
Haematoma (collection of blood outside the blood vessels)
Hydronephrosis (water inside the kidney)
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Small intestinal perforation (hole in small intestine)
Thrombocytopenia (decrease of platelets in blood)

male:

Abdominal distension
Haemoglobin decreased
Lymphocyte count decreased
Metabolic disorder (an abnormal function and pattern of body fat. insulin resistance refers to the diminished ability of cells to respond to the action of insulin in promoting the transport of the sugar glucose, from blood into muscles and other tissues)
Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)
Oedema (fluid collection in tissue)
Oedema peripheral (superficial swelling)
Deformity (disfigurement)
Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
General physical health deterioration (weak health status)

What are the common drug interactions of Felodipine and Rapamune, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal distension
Anaemia (lack of blood)
Bilirubin conjugated increased
Blood cholesterol decreased
Blood glucose increased
Blood urea increased
Glomerular filtration rate decreased
Haemoglobin decreased
Incision site pain
Kidney transplant rejection

40-49:

Alopecia (absence of hair from areas of the body)
Arthralgia (joint pain)
Deformity (disfigurement)
Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
General physical health deterioration (weak health status)
Joint range of motion decreased (disease of joint movement)
Joint stiffness
Joint swelling
Mobility decreased (ability to move is reduced)
Myosclerosis (hardening of muscle tissue)

50-59:

Anaphylactic reaction (serious allergic reaction)
Haematoma (collection of blood outside the blood vessels)
Hydronephrosis (water inside the kidney)
Thrombocytopenia (decrease of platelets in blood)

60+:

Pyrexia (fever)
Urine output decreased
Epstein-barr virus infection
Infection
Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
Pneumonia
Respiratory failure (inadequate gas exchange by the respiratory system)
Tuberculosis (a bacterial infection by mycobacterium tuberculosis)
Angioneurotic oedema (swelling that occurs just beneath the surface of the skin or mucous membranes)
Aortic calcification (aortic calcification sign of heart valve disease)

What are the existing conditions these people have? *

Vasospasm (sudden constriction of a blood vessel, reducing its diameter and flow rate): 4 people, 19.05%
Urination - Excessive Volume: 4 people, 19.05%
Red Blood Cell Count Decreased: 4 people, 19.05%
Lipids Increased (excess lipid in body): 4 people, 19.05%
Hypotension (abnormally low blood pressure): 4 people, 19.05%
Heart Disease: 4 people, 19.05%
Gastritis (inflammation of stomach): 4 people, 19.05%
Cardiomyopathy (weakening of the heart muscle): 4 people, 19.05%
Anaemia (lack of blood): 4 people, 19.05%
Nuclear Magnetic Resonance Imaging Brain: 3 people, 14.29%

* Approximation only. Some reports may have incomplete information.

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