Finacea and Profen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Finacea (azelaic acid) and Profen (ibuprofen). Common drug interactions include suicide attempt among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Finacea and Profen. It is created by eHealthMe based on reports of 97 people who take the same drugs from the FDA, and is updated regularly.

What is Finacea?

Finacea has active ingredients of azelaic acid. It is often used in rosacea. eHealthMe is studying from 2,097 Finacea users. Check the latest studies of Finacea.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

97 people who take Finacea and Profen together, and have interactions are studied.

What are the common drug interactions of Finacea and Profen, by gender? *:

female:

Suicide attempt
Alopecia (absence of hair from areas of the body)
Arthralgia (joint pain)
Autoimmune thyroiditis (form of thyroiditis associated with an autoimmune disease)
Bacterial infection
Blood alkaline phosphatase increased
Blood pressure diastolic increased
Bruxism (habitual grinding of the teeth, typically during sleep)
Cystitis (inflammation of the wall of the bladder)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

male:

Asthenia (weakness)
Nausea (feeling of having an urge to vomit)
Hepatic enzyme increased
Hepatitis (inflammation of the liver)
Hyperhidrosis (abnormally increased sweating)
Influenza
Myalgia (muscle pain)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Nasal discomfort
Pyrexia (fever)

What are the common drug interactions of Finacea and Profen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Anxiety
Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
Cholecystitis chronic (long lasting infection of gallbladder)
Diarrhoea
Emotional distress
Gallbladder injury
General physical health deterioration (weak health status)
Injury
Scar
Splenomegaly (enlargement of spleen)

20-29:

Abdominal distension
Drug effect decreased
Helicobacter infection (helicobacter pylori (h. pylori) infects stomach)
Vomiting

30-39:

Arthralgia (joint pain)
Autoimmune thyroiditis (form of thyroiditis associated with an autoimmune disease)
Blood alkaline phosphatase increased
Constipation
Diarrhoea
Epistaxis (bleed from the nose)
Gastrointestinal pain
Hypocomplementaemia
Injury
Nausea (feeling of having an urge to vomit)

40-49:

Drug ineffective
Inflammation
Insomnia (sleeplessness)
Nightmare (unpleasant dream)
Victim of abuse
Vitamin d decreased
Blood pressure increased
Chronic kidney disease
Nausea (feeling of having an urge to vomit)
Renal failure (kidney dysfunction)

50-59:

Constipation
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Drug effect decreased
Drug hypersensitivity
Fluid retention (an abnormal accumulation of fluid in the blood)
Folliculitis (infection of hair root)
Head injury
Helicobacter infection (helicobacter pylori (h. pylori) infects stomach)
Infusion related reaction
Injection site reaction

60+:

Abdominal pain upper
Drug ineffective
Dysgeusia (disorder of the sense of taste)
Headache (pain in head)
Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
Hidradenitis (chronic disease of a type of sweat gland)
Hypertension (high blood pressure)
Intestinal obstruction
Liver transplant
Nasopharyngitis (inflammation of the nasopharynx)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 26 people, 26.80%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 20 people, 20.62%
Stress And Anxiety: 7 people, 7.22%
Immunodeficiency Common Variable: 7 people, 7.22%
High Blood Pressure: 7 people, 7.22%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 6.19%
Sleep Disorder: 5 people, 5.15%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 5 people, 5.15%
Drowsiness: 5 people, 5.15%

* Approximation only. Some reports may have incomplete information.

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