Fioricet and Adipex-p drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fioricet (acetaminophen; butalbital; caffeine) and Adipex-p (phentermine hydrochloride). Common drug interactions include arthralgia among females.

The phase IV clinical study analyzes what interactions people have when they take Fioricet and Adipex-p. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Fioricet?

Fioricet has active ingredients of acetaminophen; butalbital; caffeine. It is often used in migraine. eHealthMe is studying from 12,423 Fioricet users. Check the latest studies of Fioricet.

What is Adipex-p?

Adipex-p has active ingredients of phentermine hydrochloride. It is often used in weight loss. eHealthMe is studying from 2,718 Adipex-p users. Check the latest studies of Adipex-p.

On Jul, 17, 2026

13 people who take Fioricet and Adipex-p together, and have interactions are studied.

Fioricet and Adipex-p drug interactions.

What are the common drug interactions of Fioricet and Adipex-P, by gender? *:

female:

Arthralgia (joint pain)
Chest pain
Dyspnoea (difficult or laboured respiration)
Emotional distress
Fatigue (feeling of tiredness)
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
Insomnia (sleeplessness)
Muscle spasms (muscle contraction)
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
Oedema (fluid collection in tissue)

male:

n/a

What are the common drug interactions of Fioricet and Adipex-P, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Chest pain
Decreased activity
Drug ineffective
Dyspnoea exertional (breathlessness or shortness of breath)
Insomnia (sleeplessness)
Mitral valve incompetence (inefficient heart valve)
Oedema lower limb (fluid collection in tissue of lower leg)
Pulmonary valve incompetence
Syncope (loss of consciousness with an inability to maintain postural tone)
Tricuspid valve incompetence (inefficient heart valve)

40-49:

n/a

50-59:

Arthralgia (joint pain)
Chest pain
Dry mouth
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Mitral valve incompetence (inefficient heart valve)
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
Oedema (fluid collection in tissue)
Pulmonary thrombosis (scarring in the lungs)
Tricuspid valve incompetence (inefficient heart valve)

60+:

Chills (felling of cold)
Diarrhoea
Pruritus generalised (generalized itching)
Tremor (trembling or shaking movements in one or more parts of your body)
Weight increased
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Hot flush (sudden feelings of heat)
Hyperhidrosis (abnormally increased sweating)
Insomnia (sleeplessness)
Nasopharyngitis (inflammation of the nasopharynx)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 30.77%
Wheezing (a high-pitched whistling sound made while you breath): 2 people, 15.38%
Vitamin D Decreased: 2 people, 15.38%
Anaemia Vitamin B12 Deficiency: 2 people, 15.38%
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 2 people, 15.38%
Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 2 people, 15.38%
Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 15.38%
Headache (pain in head): 2 people, 15.38%
Iron Deficiency Anaemia: 2 people, 15.38%
The Flu (the flu is caused by an influenza virus): 2 people, 15.38%

* Approximation only. Some reports may have incomplete information.

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