Fioricet and Augmentin '125' drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Fioricet (acetaminophen; butalbital; caffeine) and Augmentin '125' (amoxicillin; clavulanate potassium). Common drug interactions include pain among females and bronchitis among males.
The phase IV clinical study analyzes what interactions people have when they take Fioricet and Augmentin '125'. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.
What is Fioricet?
Fioricet has active ingredients of acetaminophen; butalbital; caffeine. It is often used in migraine. eHealthMe is studying from 12,423 Fioricet users. Check the latest studies of Fioricet.
What is Augmentin '125'?
Augmentin '125' has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 10,452 Augmentin '125' users. Check the latest studies of Augmentin '125'.
28 people who take Fioricet and Augmentin '125' together, and have interactions are studied.

What are the common drug interactions of Fioricet and Augmentin '125', by gender? *:
female:
- Pain
- Peroneal nerve palsy
- Persistent foetal circulation (baby's blood does not need to pass by the lungs)
- Talipes
- Tendinous contracture (an abnormal, often permanent shortening of tendon)
- Asthenia (weakness)
- Bone pain
- Cellulitis (infection under the skin)
- Chest discomfort
- Chest pain
male:
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Pneumonia
- Atelectasis (partial or complete collapse of the lung)
- Back pain
- Benign prostatic hyperplasia (benign enlargement of the prostate)
- Bone density decreased
- Bone disorder
- Bone erosion
- Cataract (clouding of the lens inside the eye)
- Cerebral atrophy (decrement in size of brain)
What are the common drug interactions of Fioricet and Augmentin '125', by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Cholecystitis chronic (long lasting infection of gallbladder)
- Gallbladder disorder
- Injury
- Pain
40-49:
- Anxiety disorder
- Arthralgia (joint pain)
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Asthenia (weakness)
- Back pain
- Bone pain
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Cellulitis (infection under the skin)
- Chest discomfort
- Chest pain
50-59:
- Bone pain
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Chest discomfort
- Contusion (a type of hematoma of tissue in which capillaries)
- Cough
- Dyspnoea (difficult or laboured respiration)
- Hidradenitis (chronic disease of a type of sweat gland)
- Increased tendency to bruise (increased tendency to injure the underlying soft tissue or bone)
- Injection site haematoma (localized swelling filled with blood at injection site)
- Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
60+:
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Pneumonia
- Atelectasis (partial or complete collapse of the lung)
- Back pain
- Benign prostatic hyperplasia (benign enlargement of the prostate)
- Bone density decreased
- Bone disorder
- Bone erosion
- Cataract (clouding of the lens inside the eye)
- Cerebral atrophy (decrement in size of brain)
What are the existing conditions these people have? *
- Post-Traumatic Stress Disorder: 7 people, 25.00%
- Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 5 people, 17.86%
- Nausea (feeling of having an urge to vomit): 5 people, 17.86%
- Depression: 5 people, 17.86%
- Oral Pain: 4 people, 14.29%
- Oedema (fluid collection in tissue): 4 people, 14.29%
- Multiple Myeloma (cancer of the plasma cells): 4 people, 14.29%
- Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 4 people, 14.29%
- Cough: 4 people, 14.29%
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 4 people, 14.29%
* Approximation only. Some reports may have incomplete information.
Do you take Fioricet and Augmentin '125'?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Fioricet (12,423 reports)
- Augmentin '125' (10,452 reports)
Browse all drug interactions of Fioricet and Augmentin '125':
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Fioricet:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Augmentin '125':
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Fioricet and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Augmentin '125' and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on acetaminophen; butalbital; caffeine and amoxicillin; clavulanate potassium (the active ingredients of Fioricet and Augmentin '125', respectively), and Fioricet and Augmentin '125' (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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