Florinef and Aredia drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Florinef (fludrocortisone acetate) and Aredia (pamidronate disodium). Common drug interactions include pain among females and osteomyelitis among males.

The phase IV clinical study analyzes what interactions people have when they take Florinef and Aredia. It is created by eHealthMe based on reports of 93 people who take the same drugs from the FDA, and is updated regularly.

What is Florinef?

Florinef has active ingredients of fludrocortisone acetate. It is often used in addison's disease. eHealthMe is studying from 3,834 Florinef users. Check the latest studies of Florinef.

What is Aredia?

Aredia has active ingredients of pamidronate disodium. It is often used in breast cancer. eHealthMe is studying from 15,364 Aredia users. Check the latest studies of Aredia.



On Jul, 17, 2026

93 people who take Florinef and Aredia together, and have interactions are studied.

Florinef and Aredia drug interactions.

What are the common drug interactions of Florinef and Aredia, by gender? *:

female:

  1. Pain
  2. Bone disorder
  3. Weight decreased
  4. Osteonecrosis of jaw (death of bone of jaw)
  5. Gait disturbance
  6. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  7. Arthralgia (joint pain)
  8. Infection
  9. Osteomyelitis (infection of bone)
  10. Renal failure chronic (long lasting kidney dysfunction)

male:

  1. Osteomyelitis (infection of bone)
  2. Osteonecrosis of jaw (death of bone of jaw)
  3. Impaired healing
  4. Infection
  5. Pleural effusion (water on the lungs)
  6. Anaemia (lack of blood)
  7. Asthenia (weakness)
  8. Dizziness
  9. Haemoglobin decreased
  10. Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)

What are the common drug interactions of Florinef and Aredia, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Peripheral swelling

50-59:

  1. Dysphagia (a condition in which swallowing is difficult or painful)
  2. Renal failure chronic (long lasting kidney dysfunction)
  3. Weight decreased
  4. Deafness
  5. Neuropathy peripheral (surface nerve damage)
  6. Osteonecrosis of jaw (death of bone of jaw)
  7. Gait disturbance
  8. Decreased appetite
  9. Pulmonary congestion (congestion in the lungs)
  10. Joint dislocation (a joint position is changed from normal position)

60+:

  1. Pain
  2. Osteomyelitis (infection of bone)
  3. Dyspnoea (difficult or laboured respiration)
  4. Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
  5. Constipation
  6. Headache (pain in head)
  7. Pleural effusion (water on the lungs)
  8. Chest pain
  9. Gait disturbance
  10. Weight decreased

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 41 people, 44.09%
  2. Metastases To Bone (cancer spreads to bone): 28 people, 30.11%
  3. Stress And Anxiety: 21 people, 22.58%
  4. Hypercalcaemia Of Malignancy (elevated calcium (ca+) level in the blood with cancer): 18 people, 19.35%
  5. Hypercalcaemia (elevated calcium (ca+) level in the blood): 13 people, 13.98%
  6. Light Chain Analysis Increased: 12 people, 12.90%
  7. Type 2 Diabetes: 8 people, 8.60%
  8. Neoplasm Malignant (cancer tumour): 8 people, 8.60%

* Approximation only. Some reports may have incomplete information.

Do you take Florinef and Aredia?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Florinef and Aredia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Florinef:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Aredia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Florinef and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Aredia and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on fludrocortisone acetate and pamidronate disodium (the active ingredients of Florinef and Aredia, respectively), and Florinef and Aredia (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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