Ruxience and Drug hypersensitivity - a phase IV clinical study of FDA data

Summary:

Drug hypersensitivity is reported as a side effect among people who take Ruxience (rituximab-pvvr), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Methotrexate, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Drug hypersensitivity when taking Ruxience. It is created by eHealthMe based on reports of 4,258 people who have side effects when taking Ruxience from the FDA, and is updated regularly.

What is Ruxience?

Ruxience has active ingredients of rituximab-pvvr. eHealthMe is studying from 4,260 Ruxience users. Check the latest studies of Ruxience.

What is Drug hypersensitivity?

Drug hypersensitivity is found to be associated with 2,486 drugs and 2,339 conditions by eHealthMe. Check the latest studies of Drug hypersensitivity.

On Jul, 17, 2026

4,258 people reported to have side effects when taking Ruxience.
Among them, 77 people (1.81%) have Drug hypersensitivity.

Could Ruxience cause Drug hypersensitivity?

Among these 77 people:

How long have people been on Ruxience when they have Drug hypersensitivity? *

What is the gender of people who have Drug hypersensitivity when taking Ruxience? *

female: 41.89 %
male: 58.11 %

What is the age of people who have Drug hypersensitivity when taking Ruxience? *

What are other drugs people take besides Ruxience? *

What are other side effects people have besides Drug hypersensitivity? *

Drug Ineffective: 34 people, 44.16%
Fatigue (feeling of tiredness): 33 people, 42.86%
Pain: 27 people, 35.06%
Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 23 people, 29.87%
Dizziness: 20 people, 25.97%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 18 people, 23.38%
Lymphoma (cancer that begins in immune system cells): 18 people, 23.38%
Joint Range Of Motion Decreased (disease of joint movement): 18 people, 23.38%
High Blood Pressure: 18 people, 23.38%
Nausea (feeling of having an urge to vomit): 16 people, 20.78%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 60 people, 77.92%
High Blood Pressure: 11 people, 14.29%
Itching: 5 people, 6.49%
Glomerulonephritis Minimal Lesion (a disease of the kidney that causes nephrotic syndrome and usually affects children): 3 people, 3.90%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 2 people, 2.60%
Polymyositis (inflammatory muscle disease that causes weakness of the skeletal muscles): 2 people, 2.60%
Lymphoplasmacytoid Lymphoma/immunocytoma (a cancer of the lymphatic system): 2 people, 2.60%
Blood Pressure Abnormal: 2 people, 2.60%
Waldenstrom's Macroglobulinaemia (cancer affects small lymphocytes (white blood cells)): 1 person, 1.30%
Microscopic Polyangiitis (inflammation involving multiple blood or lymph small-vessel): 1 person, 1.30%

* Approximation only. Some reports may have incomplete information.

Do you take Ruxience and have Drug hypersensitivity?

- Check whether Drug hypersensitivity is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ruxience:

Ruxience (4,260 reports)

Browse all side effects of Ruxience:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Drug hypersensitivity:

Drug hypersensitivity (2,486 drugs)

Browse all the conditions that are associated with Drug hypersensitivity:

Drug hypersensitivity (2,339 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on rituximab-pvvr (the active ingredients of Ruxience) and Ruxience (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.