Fiorinal and Gammagard drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fiorinal (aspirin; butalbital; caffeine) and Gammagard (immune globulin). Common drug interactions include cystitis among females.

The phase IV clinical study analyzes what interactions people have when they take Fiorinal and Gammagard. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Fiorinal?

Fiorinal has active ingredients of aspirin; butalbital; caffeine. It is often used in migraine. eHealthMe is studying from 2,714 Fiorinal users. Check the latest studies of Fiorinal.

What is Gammagard?

Gammagard has active ingredients of immune globulin. eHealthMe is studying from 8,948 Gammagard users. Check the latest studies of Gammagard.



On Jul, 27, 2026

19 people who take Fiorinal and Gammagard together, and have interactions are studied.

Fiorinal and Gammagard drug interactions.

What are the common drug interactions of Fiorinal and Gammagard, by gender? *:

female:

  1. Cystitis (inflammation of the wall of the bladder)
  2. Influenza
  3. Injection site warmth
  4. Ear infection
  5. Infusion site pruritus (severe itching at infusion site)
  6. Infusion site rash
  7. Infusion site urticaria (rash of round, red welts on the skin at infusion site)
  8. Dysphagia (a condition in which swallowing is difficult or painful)
  9. Weight decreased
  10. Ear discomfort

male:

n/a

What are the common drug interactions of Fiorinal and Gammagard, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Viral infection

40-49:

n/a

50-59:

n/a

60+:

  1. Cellulitis (infection under the skin)
  2. Infusion site erythema (reddening of the skin at infusion site)
  3. Infusion site pruritus (severe itching at infusion site)
  4. Infusion site rash
  5. Infusion site urticaria (rash of round, red welts on the skin at infusion site)
  6. Seasonal allergy (allergic condition due to certain season)
  7. Dysphagia (a condition in which swallowing is difficult or painful)
  8. Sinusitis (inflammation of sinus)
  9. Weight decreased

What are the existing conditions these people have? *

  1. Immunodeficiency Common Variable: 15 people, 78.95%
  2. Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 3 people, 15.79%
  3. Lambert-Eaton Syndrome (this means your immune system mistakenly targets healthy cells and tissues in the body): 3 people, 15.79%
  4. Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 2 people, 10.53%
  5. Chronic Inflammatory Demyelinating Polyradiculoneuropathy (long lasting infection of nerves outside brain and spinal cord): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Fiorinal and Gammagard?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Fiorinal and Gammagard:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Fiorinal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Gammagard:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Fiorinal and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Gammagard and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on aspirin; butalbital; caffeine and immune globulin (the active ingredients of Fiorinal and Gammagard, respectively), and Fiorinal and Gammagard (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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