Fiorinal and Yasmin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fiorinal (aspirin; butalbital; caffeine) and Yasmin (drospirenone; ethinyl estradiol). Common drug interactions include pain among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Fiorinal and Yasmin. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Fiorinal?

Fiorinal has active ingredients of aspirin; butalbital; caffeine. It is often used in migraine. eHealthMe is studying from 2,714 Fiorinal users. Check the latest studies of Fiorinal.

What is Yasmin?

Yasmin has active ingredients of drospirenone; ethinyl estradiol. It is often used in birth control. eHealthMe is studying from 48,855 Yasmin users. Check the latest studies of Yasmin.

On Jul, 30, 2026

21 people who take Fiorinal and Yasmin together, and have interactions are studied.

What are the common drug interactions of Fiorinal and Yasmin, by gender? *:

female:

Pain
Pulmonary embolism (blockage of the main artery of the lung)
Anxiety
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Emotional distress
General physical health deterioration (weak health status)
Nausea (feeling of having an urge to vomit)
Vomiting
Abdominal pain

male:

Anaemia (lack of blood)
Anxiety
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Superior sagittal sinus thrombosis (blood clot in the dural venous sinuses, which drain blood from the brain)
Thrombocytopenia (decrease of platelets in blood)
Transverse sinus thrombosis (a blood clot in transverse sinus)
Atelectasis (partial or complete collapse of the lung)
Delirium (wild excitement)
Emotional distress
General physical health deterioration (weak health status)

What are the common drug interactions of Fiorinal and Yasmin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Depression
Diarrhoea
Emotional distress
Hyperhidrosis (abnormally increased sweating)
Hyperventilation
Hypotension (abnormally low blood pressure)
International normalised ratio increased
Lip swelling
Listless (lack of interest, energy, or spirit)

30-39:

Pain
Abdominal pain
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Cholecystitis chronic (long lasting infection of gallbladder)
Pulmonary embolism (blockage of the main artery of the lung)
Anxiety
Dry throat
Dysphagia (a condition in which swallowing is difficult or painful)
Emotional distress
Oropharyngeal pain

40-49:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Pain
Pulmonary embolism (blockage of the main artery of the lung)
Anxiety
Emotional distress
Injury
Depression
General physical health deterioration (weak health status)
Abdominal pain upper
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)

50-59:

Agitation (state of anxiety or nervous excitement)
Balance disorder
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Coma (state of unconsciousness lasting more than six hours)
Confusional state
Delusion (a false belief or opinion)
Depression
General physical health deterioration (weak health status)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Pain

60+:

Anaemia (lack of blood)
Anxiety
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Superior sagittal sinus thrombosis (blood clot in the dural venous sinuses, which drain blood from the brain)
Thrombocytopenia (decrease of platelets in blood)
Transverse sinus thrombosis (a blood clot in transverse sinus)
Atelectasis (partial or complete collapse of the lung)
Delirium (wild excitement)
Emotional distress
General physical health deterioration (weak health status)

What are the existing conditions these people have? *

Pain: 4 people, 19.05%
Depression: 3 people, 14.29%
Asthma: 3 people, 14.29%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 9.52%
High Blood Pressure: 2 people, 9.52%
Headache (pain in head): 2 people, 9.52%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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