Firazyr and Seroquel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Firazyr (icatibant acetate) and Seroquel (quetiapine fumarate). Common drug interactions include hereditary angioedema among females and hereditary angioedema among males.

The phase IV clinical study analyzes what interactions people have when they take Firazyr and Seroquel. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.

What is Firazyr?

Firazyr has active ingredients of icatibant acetate. eHealthMe is studying from 5,650 Firazyr users. Check the latest studies of Firazyr.

What is Seroquel?

Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. eHealthMe is studying from 120,287 Seroquel users. Check the latest studies of Seroquel.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

45 people who take Firazyr and Seroquel together, and have interactions are studied.

What are the common drug interactions of Firazyr and Seroquel, by gender? *:

female:

Hereditary angioedema (recurrent episodes of severe swelling)
Malaise (a feeling of general discomfort or uneasiness)
Eye infection
Sinusitis (inflammation of sinus)
Upper respiratory tract infection
Headache (pain in head)
Pneumonia
Epistaxis (bleed from the nose)
Vomiting
Bacterial infection

male:

Hereditary angioedema (recurrent episodes of severe swelling)
Pulmonary embolism (blockage of the main artery of the lung)
Catheter site erythema (redness of skin at catheter site)
Chest pain
Drug ineffective
Dysphonia (speech disorder attributable to a disorder of phonation)
Injection site pain
Pain
Pyrexia (fever)
Thrombosis (formation of a blood clot inside a blood vessel)

What are the common drug interactions of Firazyr and Seroquel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Hereditary angioedema (recurrent episodes of severe swelling)
Myalgia (muscle pain)
Chest pain
Contusion (a type of hematoma of tissue in which capillaries)
Headache (pain in head)
Swelling
Pain
Pulmonary embolism (blockage of the main artery of the lung)
Anaphylactic reaction (serious allergic reaction)
Coma (state of unconsciousness lasting more than six hours)

40-49:

Hereditary angioedema (recurrent episodes of severe swelling)
Pneumonia
Asthma
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Drug ineffective
Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)

50-59:

Depressed mood
Eye infection
Upper respiratory tract infection
Vomiting
Infection
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Concussion (short loss of normal brain function in response to a head injury)
Memory impairment
Balance disorder
Gait disturbance

60+:

n/a

What are the existing conditions these people have? *

Hereditary Angioedema (recurrent episodes of severe swelling): 40 people, 88.89%
Immune System Disorder: 16 people, 35.56%
Immunodeficiency Common Variable: 5 people, 11.11%
Hypersensitivity: 3 people, 6.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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