Firazyr and Valium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Firazyr (icatibant acetate) and Valium (diazepam). Common drug interactions include hypoaesthesia among females and hereditary angioedema among males.

The phase IV clinical study analyzes what interactions people have when they take Firazyr and Valium. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Firazyr?

Firazyr has active ingredients of icatibant acetate. eHealthMe is studying from 5,650 Firazyr users. Check the latest studies of Firazyr.

What is Valium?

Valium has active ingredients of diazepam. It is often used in stress and anxiety. eHealthMe is studying from 48,647 Valium users. Check the latest studies of Valium.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 24, 2026

38 people who take Firazyr and Valium together, and have interactions are studied.

What are the common drug interactions of Firazyr and Valium, by gender? *:

female:

Hypoaesthesia (reduced sense of touch or sensation)
Migraine (headache)
Sinusitis (inflammation of sinus)
Transfusion reaction (a serious problem that occurs after a patient receives a transfusion of blood)
Tremor (trembling or shaking movements in one or more parts of your body)
Trigeminal neuralgia (a painful condition of the nerve responsible for most facial sensation)
Abdominal pain
Balance disorder
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chest discomfort

male:

Hereditary angioedema (recurrent episodes of severe swelling)
Nasopharyngitis (inflammation of the nasopharynx)

What are the common drug interactions of Firazyr and Valium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Urinary incontinence (inability to control the flow of urine and involuntary urination)
Urinary tract infection
Visual impairment
Vomiting
Weight decreased
Asthenia (weakness)
Fall
Gait disturbance
Hypoaesthesia (reduced sense of touch or sensation)
Abdominal pain

30-39:

Bacterial infection
Device related infection
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hereditary angioedema (recurrent episodes of severe swelling)
Laryngeal oedema (swelling of larynx)
Pneumonia
Rectal ulcer (ulcer of rectum)

40-49:

Dyspnoea (difficult or laboured respiration)
Intestinal obstruction
Migraine (headache)
Sinusitis (inflammation of sinus)
Transfusion reaction (a serious problem that occurs after a patient receives a transfusion of blood)
Tremor (trembling or shaking movements in one or more parts of your body)
Trigeminal neuralgia (a painful condition of the nerve responsible for most facial sensation)
Device related infection
Poisoning
Abdominal pain lower

50-59:

Fall
Hepatitis (inflammation of the liver)
Hereditary angioedema (recurrent episodes of severe swelling)
Impaired gastric emptying
Nausea (feeling of having an urge to vomit)
Pancreatitis (inflammation of pancreas)
Chest discomfort
Dizziness
Headache (pain in head)
Pancreatitis acute (sudden inflammation of pancreas)

60+:

Balance disorder
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dizziness
Fall
Hereditary angioedema (recurrent episodes of severe swelling)

What are the existing conditions these people have? *

Hereditary Angioedema (recurrent episodes of severe swelling): 31 people, 81.58%
Asthma: 5 people, 13.16%
Immune System Disorder: 4 people, 10.53%
Migraine (headache): 3 people, 7.89%
Immunodeficiency Common Variable: 3 people, 7.89%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 7.89%
Angioedema (rapid swelling of the dermis): 3 people, 7.89%
Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 3 people, 7.89%
Urticaria (rash of round, red welts on the skin that itch intensely): 2 people, 5.26%
Pain: 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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