Flagyl and Mucomyst drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flagyl (metronidazole) and Mucomyst (acetylcysteine). Common drug interactions include abdominal pain among females and cholestasis among males.

The phase IV clinical study analyzes what interactions people have when they take Flagyl and Mucomyst. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Flagyl?

Flagyl has active ingredients of metronidazole. It is often used in vaginitis bacterial. eHealthMe is studying from 25,897 Flagyl users. Check the latest studies of Flagyl.

What is Mucomyst?

Mucomyst has active ingredients of acetylcysteine. eHealthMe is studying from 1,835 Mucomyst users. Check the latest studies of Mucomyst.

On Jul, 15, 2026

47 people who take Flagyl and Mucomyst together, and have interactions are studied.

What are the common drug interactions of Flagyl and Mucomyst, by gender? *:

female:

Abdominal pain
Acute myocardial infarction (acute heart attack)
Aggression
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Atelectasis (partial or complete collapse of the lung)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Cerebral atrophy (decrement in size of brain)

male:

Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Infection
Hypertension (high blood pressure)
Injury
Pain
Pneumonia
Renal injury (kidney injury)
Sepsis (a severe blood infection that can lead to organ failure and death)
Abdominal pain
Emotional distress

What are the common drug interactions of Flagyl and Mucomyst, by age (0-1 to 60+)? *:

0-1:

Drug ineffective
Haemoglobin decreased
Haemorrhage (bleeding)

2-9:

Hypertension (high blood pressure)
Infection
Acinetobacter infection (infection by group of bacteria commonly found in soil and water)
Diarrhoea haemorrhagic (bloody diarrhoea)
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Haematoma (collection of blood outside the blood vessels)
Pleural effusion (water on the lungs)
Pyrexia (fever)
Septic shock (shock due to blood infection)
Tooth abscess (pus formation in tooth)

10-19:

n/a

20-29:

Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Febrile neutropenia (fever with reduced white blood cells)
Gastrointestinal toxicity (damage to digestive tract by any substance)
Lung infection
Neutropenia (an abnormally low number of neutrophils)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pleural effusion (water on the lungs)
Pneumonia
Pseudomonal sepsis (pseudomonas infections are diseases caused by a bacterium from the genus pseudomonas)
Pyrexia (fever)

30-39:

Abdominal pain
Acute respiratory failure
Back pain
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chronic respiratory failure
Dyslipidaemia (abnormal amount of lipids)
Electrocardiogram qt prolonged
Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
Fluid overload (too much fluid in the blood)
Hypokalaemia (low potassium)

40-49:

Abdominal pain
Pancreatic necrosis (death of pancreas tissue in pancreas)
Pancreatitis acute (sudden inflammation of pancreas)

50-59:

Emotional distress
Stress
Cardiac disorder
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Death
Depression
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Organ failure
Psychiatric symptom
Anhedonia (inability to experience pleasure from activities usually found enjoyable)

60+:

Blood creatinine increased
Fluid retention (an abnormal accumulation of fluid in the blood)
Emotional distress
Fear
Haemoglobin decreased
Injury
Multi-organ failure (multisystem organ failure)
Renal injury (kidney injury)
Neutropenia (an abnormally low number of neutrophils)
Pyrexia (fever)

What are the existing conditions these people have? *

Pneumonia: 5 people, 10.64%
Pain: 5 people, 10.64%
Hypotension (abnormally low blood pressure): 4 people, 8.51%
Respiratory Tract Oedema (swelling of respiratory tract due to excess fluid collection in tissue): 3 people, 6.38%
Immunodeficiency Disorders: 3 people, 6.38%
Hypokalemia (low potassium): 3 people, 6.38%
Hypocalcaemia (levels of calcium in blood serum are abnormally low): 3 people, 6.38%
Hairy Cell Leukaemia (a type of blood cancer): 3 people, 6.38%
Fever: 3 people, 6.38%
Constipation: 3 people, 6.38%

* Approximation only. Some reports may have incomplete information.

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