Flaxseed and Amitiza drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flaxseed (flaxseed) and Amitiza (lubiprostone). Common drug interactions include infection among females and infective pulmonary exacerbation of cystic fibrosis among males.

The phase IV clinical study analyzes what interactions people have when they take Flaxseed and Amitiza. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.

What is Flaxseed?

Flaxseed has active ingredients of flaxseed. It is often used in high blood cholesterol. eHealthMe is studying from 7,137 Flaxseed users. Check the latest studies of Flaxseed.

What is Amitiza?

Amitiza has active ingredients of lubiprostone. It is often used in constipation. eHealthMe is studying from 10,567 Amitiza users. Check the latest studies of Amitiza.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

55 people who take Flaxseed and Amitiza together, and have interactions are studied.

What are the common drug interactions of Flaxseed and Amitiza, by gender? *:

female:

Infection
Initial insomnia (feeling of inadequate or poor-quality sleep)
Injection site pruritus (severe itching at injection site)
Injection site urticaria (rash of round, red welts on the skin at injection site)
Nausea (feeling of having an urge to vomit)
Road traffic accident
Weight increased
Anaemia (lack of blood)
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Fall

male:

Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
Nail infection
Sinusitis (inflammation of sinus)

What are the common drug interactions of Flaxseed and Amitiza, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)

20-29:

Infection
Injection site pruritus (severe itching at injection site)
Injection site urticaria (rash of round, red welts on the skin at injection site)
Sinusitis (inflammation of sinus)
Headache (pain in head)
Injection site bruising
Nausea (feeling of having an urge to vomit)
Oral candidiasis (fungal infection of mouth)
Vomiting
Withdrawal bleed (bleeding occurs between periods)

30-39:

n/a

40-49:

Bipolar disorder (mood disorder)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Hypoxia (low oxygen in tissues)
Road traffic accident
Hepatic rupture (rapture of common benign tumour of liver)
Pelvic floor dyssynergia (problem with the way certain nerves and muscles function in the pelvic floor)
Liver injury

50-59:

Fatigue (feeling of tiredness)
Actinic keratosis (skin disease due to sun exposure)
Agitation (state of anxiety or nervous excitement)
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Bowen's disease (early stage of skin cancer)
Drug ineffective
Insomnia (sleeplessness)
Muscle strain (an injury to a muscle in which the muscle fibres tear)
Squamous cell carcinoma of skin (a cancer of a kind of epithelial cell, the squamous cell. these cells are the main part of the epidermis of the skin)

60+:

Dizziness
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Memory impairment
Vision blurred
Activities of daily living impaired
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Device occlusion
Diarrhoea
Diplopia (double vision)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 27 people, 49.09%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 17 people, 30.91%
Fibromyalgia (a long-term condition which causes pain all over the body): 6 people, 10.91%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 9.09%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 9.09%
Immune System Disorder: 4 people, 7.27%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 3 people, 5.45%
High Blood Pressure: 3 people, 5.45%

* Approximation only. Some reports may have incomplete information.

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