Flaxseed and Welchol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flaxseed (flaxseed) and Welchol (colesevelam hydrochloride). Common drug interactions include paraesthesia among females and panic attack among males.

The phase IV clinical study analyzes what interactions people have when they take Flaxseed and Welchol. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.

What is Flaxseed?

Flaxseed has active ingredients of flaxseed. It is often used in high blood cholesterol. eHealthMe is studying from 7,137 Flaxseed users. Check the latest studies of Flaxseed.

What is Welchol?

Welchol has active ingredients of colesevelam hydrochloride. It is often used in high blood cholesterol. eHealthMe is studying from 11,309 Welchol users. Check the latest studies of Welchol.

On Jul, 15, 2026

45 people who take Flaxseed and Welchol together, and have interactions are studied.

What are the common drug interactions of Flaxseed and Welchol, by gender? *:

female:

Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Parosmia (distortion of the sense of smell, as in smelling odours that are not present)
Protein urine present
Pruritus (severe itching of the skin)
Pseudomembranous colitis (antibiotic-associated diarrhoea (aad), is an infection of the colon)
Pulmonary oedema (fluid accumulation in the lungs)
Pyrexia (fever)
Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly)
Renal failure (kidney dysfunction)
Respiratory failure (inadequate gas exchange by the respiratory system)

male:

Panic attack
Weight decreased
Dehydration (dryness resulting from the removal of water)
Device related infection
Drug hypersensitivity
Drug ineffective
Dyschezia (difficulty in defecating)
Dysuria (painful or difficult urination)
Faeces hard
Fluid retention (an abnormal accumulation of fluid in the blood)

What are the common drug interactions of Flaxseed and Welchol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Ill-defined disorder
Malaise (a feeling of general discomfort or uneasiness)
Memory impairment
Mobility decreased (ability to move is reduced)
Vitamin b complex deficiency
Balance disorder
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Fatigue (feeling of tiredness)
Flushing (the warm, red condition of human skin)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)

50-59:

Blood glucose increased
Glycosylated haemoglobin increased
Injection site nodule (small swelling or aggregation of cells in the body, esp. an abnormal one at injection site)
Weight decreased
Drug hypersensitivity
Bladder pain
Contusion (a type of hematoma of tissue in which capillaries)
Creatinine renal clearance increased
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)

60+:

Panic attack
Nausea (feeling of having an urge to vomit)
Ascites (accumulation of fluid in the abdominal cavity)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Back pain
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Cardiac flutter (abnormal heart rhythm)
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Colitis ischaemic (due to infection of intestine impaired blood supply to colon)

What are the existing conditions these people have? *

Neuropathy Peripheral (surface nerve damage): 7 people, 15.56%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 15.56%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 11.11%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 11.11%
Type 2 Diabetes: 4 people, 8.89%
Multiple Myeloma (cancer of the plasma cells): 3 people, 6.67%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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