Zolpidem and Tenex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zolpidem (zolpidem tartrate) and Tenex (guanfacine hydrochloride). Common drug interactions include osteoporosis among females and psoriatic arthropathy among males.

The phase IV clinical study analyzes what interactions people have when they take Zolpidem and Tenex. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Zolpidem?

Zolpidem has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 92,695 Zolpidem users. Check the latest studies of Zolpidem.

What is Tenex?

Tenex has active ingredients of guanfacine hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 1,865 Tenex users. Check the latest studies of Tenex.

On Jul, 15, 2026

21 people who take Zolpidem and Tenex together, and have interactions are studied.

What are the common drug interactions of Zolpidem and Tenex, by gender? *:

female:

Osteoporosis (bones weak and more likely to break)
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Diabetic coma
Pancreatitis (inflammation of pancreas)
Therapeutic response unexpected
Type 2 diabetes mellitus
Acute myocardial infarction (acute heart attack)
Chest pain
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)

male:

Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Psoriasis (immune-mediated disease that affects the skin)
Hepatic steatosis (fatty liver disease)
Hypersensitivity
Incontinence (lack of moderation or self-control)
Mania (a state of abnormally elevated or irritable mood)
Pain in extremity
Pancreatitis (inflammation of pancreas)
Pneumonia
Rash macular (small, flat red spots)

What are the common drug interactions of Zolpidem and Tenex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal distension
Activities of daily living impaired
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Dry mouth
Dyspepsia (indigestion)
Gait disturbance
Incontinence (lack of moderation or self-control)
Mania (a state of abnormally elevated or irritable mood)
Rash macular (small, flat red spots)
Somnolence (a state of near-sleep, a strong desire for sleep)

30-39:

n/a

40-49:

Somnolence (a state of near-sleep, a strong desire for sleep)
Chronic kidney disease

50-59:

Pancreatitis (inflammation of pancreas)
Pneumonia

60+:

Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Psoriasis (immune-mediated disease that affects the skin)
Depression
Drug ineffective
Hepatic steatosis (fatty liver disease)
Hypersensitivity
Pain in extremity

What are the existing conditions these people have? *

Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 8 people, 38.10%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 33.33%
Pain: 3 people, 14.29%
Stress And Anxiety: 2 people, 9.52%
Stomatitis (inflammation of mucous membrane of mouth): 2 people, 9.52%
Sleep Disorder: 2 people, 9.52%
Renal Cell Carcinoma (a kidney cancer): 2 people, 9.52%
Nasopharyngitis (inflammation of the nasopharynx): 2 people, 9.52%
Joint Pain: 2 people, 9.52%
Head Injury: 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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