Flector and Levothyroxine sodium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flector (diclofenac epolamine) and Levothyroxine sodium (levothyroxine sodium). Common drug interactions include arthralgia among females and epilepsy among males.

The phase IV clinical study analyzes what interactions people have when they take Flector and Levothyroxine sodium. It is created by eHealthMe based on reports of 64 people who take the same drugs from the FDA, and is updated regularly.

What is Flector?

Flector has active ingredients of diclofenac epolamine. It is often used in pain. eHealthMe is studying from 5,112 Flector users. Check the latest studies of Flector.

What is Levothyroxine sodium?

Levothyroxine sodium has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 129,812 Levothyroxine sodium users. Check the latest studies of Levothyroxine sodium.



On Jul, 07, 2026

64 people who take Flector and Levothyroxine sodium together, and have interactions are studied.

Flector and Levothyroxine sodium drug interactions.

What are the common drug interactions of Flector and Levothyroxine Sodium, by gender? *:

female:

  1. Arthralgia (joint pain)
  2. Diarrhoea
  3. Drug ineffective
  4. Hyperkalaemia (damage to or disease of the kidney)
  5. Renal failure (kidney dysfunction)
  6. Dizziness
  7. Dehydration (dryness resulting from the removal of water)
  8. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  9. Pain in extremity
  10. Tremor (trembling or shaking movements in one or more parts of your body)

male:

  1. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
  2. Fatigue (feeling of tiredness)
  3. Influenza like illness
  4. Lethargy (tiredness)
  5. Malaise (a feeling of general discomfort or uneasiness)
  6. Memory impairment
  7. Urticaria (rash of round, red welts on the skin that itch intensely)
  8. Pain in extremity
  9. Peptic ulcer perforation

What are the common drug interactions of Flector and Levothyroxine Sodium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
  2. Memory impairment
  3. Drug ineffective

50-59:

  1. Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
  2. Dyspnoea (difficult or laboured respiration)
  3. Facial bones fracture (bone fracture of face)
  4. Fall
  5. Gastric ulcer (stomach ulcer)
  6. Hyperkalaemia (damage to or disease of the kidney)
  7. Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions)
  8. Infusion site erythema (reddening of the skin at infusion site)
  9. Infusion site oedema (swelling from excessive accumulation of watery fluid from infusion site)
  10. Joint swelling

60+:

  1. Headache (pain in head)
  2. Diarrhoea
  3. Blood pressure fluctuation
  4. Body height decreased
  5. Constipation
  6. Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
  7. Hypoaesthesia (reduced sense of touch or sensation)
  8. Injection site haemorrhage (bleeding from injection site)
  9. Local swelling (swelling at the site of some application of substance or injury)
  10. Mobility decreased (ability to move is reduced)

What are the existing conditions these people have? *

  1. Osteoporosis (bones weak and more likely to break): 6 people, 9.38%
  2. High Blood Cholesterol: 6 people, 9.38%
  3. Joint Pain: 5 people, 7.81%
  4. Immunodeficiency Common Variable: 5 people, 7.81%
  5. Pain In Extremity: 4 people, 6.25%
  6. Insomnia (sleeplessness): 4 people, 6.25%
  7. Hypersensitivity: 4 people, 6.25%
  8. High Blood Pressure: 4 people, 6.25%
  9. Back Pain: 4 people, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Flector and Levothyroxine sodium?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Flector and Levothyroxine sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Flector:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Levothyroxine sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Flector and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Levothyroxine sodium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on diclofenac epolamine and levothyroxine sodium (the active ingredients of Flector and Levothyroxine sodium, respectively), and Flector and Levothyroxine sodium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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