Flexeril and Amitriptyline hydrochloride drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Flexeril (cyclobenzaprine hydrochloride) and Amitriptyline hydrochloride (amitriptyline hydrochloride). Common drug interactions include mobility decreased among females and renal failure among males.
The phase IV clinical study analyzes what interactions people have when they take Flexeril and Amitriptyline hydrochloride. It is created by eHealthMe based on reports of 109 people who take the same drugs from the FDA, and is updated regularly.
What is Flexeril?
Flexeril has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. eHealthMe is studying from 38,308 Flexeril users. Check the latest studies of Flexeril.
What is Amitriptyline hydrochloride?
Amitriptyline hydrochloride has active ingredients of amitriptyline hydrochloride. It is often used in migraine. eHealthMe is studying from 20,054 Amitriptyline hydrochloride users. Check the latest studies of Amitriptyline hydrochloride.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
109 people who take Flexeril and Amitriptyline hydrochloride together, and have interactions are studied.
What are the common drug interactions of Flexeril and Amitriptyline hydrochloride, by gender? *
What are the common drug interactions of Flexeril and Amitriptyline hydrochloride, by age (0-1 to 60+)? *
What are the existing conditions these people have? *
* Approximation only. Some reports may have incomplete information.
Do you take Flexeril and Amitriptyline hydrochloride?
- Personalize this study to your gender, age, symptoms and drugs
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Flexeril (38,308 reports)
- Amitriptyline hydrochloride (20,054 reports)
Browse all drug interactions of Flexeril and Amitriptyline hydrochloride:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Flexeril:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Amitriptyline hydrochloride:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Flexeril and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Amitriptyline hydrochloride and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Li W, Lamichhane J, "From Heartbreak to Left Bundle Branch Block: A Case of Amitriptyline Overdose", American Journal of Therapeutics, 2017 Sep .
- Li W, Lamichhane J, "From Heartbreak to Left Bundle Branch Block: A Case of Amitriptyline Overdose", American Journal of Therapeutics, 2017 Sep .
How the study uses the data?
The study uses data from the FDA. It is based on cyclobenzaprine hydrochloride and amitriptyline hydrochloride (the active ingredients of Flexeril and Amitriptyline hydrochloride, respectively), and Flexeril and Amitriptyline hydrochloride (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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