Flexeril and Calcium gluconate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flexeril (cyclobenzaprine hydrochloride) and Calcium gluconate (calcium). Common drug interactions include cough among females and febrile neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Flexeril and Calcium gluconate. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Flexeril?

Flexeril has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. eHealthMe is studying from 38,308 Flexeril users. Check the latest studies of Flexeril.

What is Calcium gluconate?

Calcium gluconate has active ingredients of calcium. eHealthMe is studying from 6,181 Calcium gluconate users. Check the latest studies of Calcium gluconate.

On Jul, 19, 2026

24 people who take Flexeril and Calcium gluconate together, and have interactions are studied.

Flexeril and Calcium gluconate drug interactions.

What are the common drug interactions of Flexeril and Calcium Gluconate, by gender? *:

female:

Cough
General physical health deterioration (weak health status)
Hypertension (high blood pressure)
Left ventricular dysfunction
Lung disorder (lung disease)
Mitral valve calcification (calcium deposit in mitral valve)
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Retinal vascular occlusion (a blockage of the small veins that carry blood away from the retina)
Sensation of foreign body
Sensation of heaviness

male:

Febrile neutropenia (fever with reduced white blood cells)
Pneumonia
Blood bicarbonate decreased
Blood creatinine increased
Blood magnesium decreased
Blood pressure increased
Colitis (inflammation of colon)
Dehydration (dryness resulting from the removal of water)
Drug ineffective
Dry skin

What are the common drug interactions of Flexeril and Calcium Gluconate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Post procedural complication
Procedural pain
Psoriasis (immune-mediated disease that affects the skin)
Retinal vascular occlusion (a blockage of the small veins that carry blood away from the retina)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)
Abdominal pain
Acute respiratory distress syndrome
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anaemia (lack of blood)

50-59:

Asthma
Colitis (inflammation of colon)
Cough
Dyspnoea (difficult or laboured respiration)
Lung disorder (lung disease)
Platelet count decreased
Sensation of foreign body
Sensation of heaviness
Sensation of pressure

60+:

Febrile neutropenia (fever with reduced white blood cells)
Vomiting
Cardiogenic shock (inadequate circulation of blood)
Chest pain
Cholecystitis acute (rapid infection of gallbladder)
Congestive cardiomyopathy (weakening of heart muscle)
Decreased appetite
Fatigue (feeling of tiredness)
General physical health deterioration (weak health status)
Hyperbilirubinaemia (excess of bilirubin in the blood)

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 10 people, 41.67%
Multiple Myeloma (cancer of the plasma cells): 10 people, 41.67%
Pain: 9 people, 37.50%
High Blood Pressure: 8 people, 33.33%
Insomnia (sleeplessness): 6 people, 25.00%
Osteoporosis (bones weak and more likely to break): 5 people, 20.83%
Oedema (fluid collection in tissue): 5 people, 20.83%
Infection: 5 people, 20.83%
Indigestion: 5 people, 20.83%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 20.83%

* Approximation only. Some reports may have incomplete information.

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