Flexeril and Diprivan drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Flexeril and Diprivan. Common interactions include sepsis among females and anxiety among males.
The phase IV clinical study analyzes what interactions people who take Flexeril and Diprivan have. It is created by eHealthMe based on reports of 52 people who take Flexeril and Diprivan from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
52 people who take Flexeril and Diprivan together, and have interactions are studied.
What is Flexeril?
Flexeril has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. eHealthMe is studying from 36,909 Flexeril users for its effectiveness, alternative drugs and more.
What is Diprivan?
Diprivan has active ingredients of propofol. eHealthMe is studying from 6,276 Diprivan users for its effectiveness, alternative drugs and more.
Number of Flexeril and Diprivan reports submitted per year:

Common Flexeril and Diprivan drug interactions by gender *:
female:
- Sepsis
- Appendicitis
- Aptyalism
- Asthma
- Bone disorder
- Bone erosion
- Bone fragmentation
- Bone pain
- Bronchopneumonia
- Cellulitis
male:
- Anxiety
- Depression
- Bronchitis
- Chronic obstructive pulmonary disease
- Colon adenoma
- Constipation
- Decreased appetite
- Device related infection
- Dysphagia
- Emotional distress
Common Flexeril and Diprivan drug interactions by age *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Acute myocardial infarction
- Acute respiratory distress syndrome
- Anaemia
- Blastomycosis
- Blood creatinine increased
- Bradycardia
- Cardiac enzymes increased
- Fluid overload
- Headache
- Hepatic enzyme increased
40-49:
- Encephalopathy
- Embolism
- Oedema peripheral
- Colorectal cancer metastatic
- Retroperitoneal lymphadenopathy
- Venous occlusion
- Venous thrombosis
- Abdominal distension
- Abdominal pain
- Device dislocation
50-59:
- Nausea
- Lumbar spinal stenosis
- Platelet count increased
- Hypoaesthesia
- Rectal haemorrhage
- Device failure
- Nasal congestion
- Scab
- Tooth extraction
- Hypogammaglobulinaemia
60+:
- Chronic kidney disease
- Renal failure
- Anxiety
- Bipolar disorder
- Depression
- Dyspnoea
- Fall
- Hyperparathyroidism secondary
- Ileus
- Nephrogenic anaemia
Common conditions people have *:
- Osteoporosis (bones weak and more likely to break): 28 people, 53.85%
- Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 27 people, 51.92%
- Pain: 16 people, 30.77%
- Thrombocytopenia (decrease of platelets in blood): 12 people, 23.08%
- Nausea And Vomiting: 7 people, 13.46%
- Nausea (feeling of having an urge to vomit): 7 people, 13.46%
- High Blood Pressure: 6 people, 11.54%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 11.54%
- Depression: 6 people, 11.54%
- Breakthrough Pain: 5 people, 9.62%
* Approximation only. Some reports may have incomplete information.
Do you take Flexeril and Diprivan?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Alternative drugs to, pros and cons of the 2 drugs:
Common Flexeril and Diprivan interactions:
- Pain: 32 reports
- Abdominal pain: 28 reports
Browse all drug interactions of Flexeril and Diprivan:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Flexeril side effects:
- Pain: 4,126 reports
- Fatigue (feeling of tiredness): 3,092 reports
- Stress and anxiety: 2,879 reports
- Headache (pain in head): 2,664 reports
- Depression: 2,304 reports
Browse all side effects of Flexeril:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Diprivan side effects:
- Hypotension (abnormally low blood pressure): 836 reports
- Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 718 reports
- Arrhythmias (irregular heartbeat): 325 reports
- Rashes (redness): 321 reports
- Fever: 298 reports
Browse all side effects of Diprivan:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Flexeril interactions:
- Flexeril and Aspirin: 4,393 reports
- Flexeril and Lyrica: 3,969 reports
- Flexeril and Xanax: 3,636 reports
- Flexeril and Prednisone: 3,575 reports
- Flexeril and Neurontin: 3,554 reports
- Flexeril and Gabapentin: 3,536 reports
- Flexeril and Nexium: 3,322 reports
- Flexeril and Cymbalta: 3,308 reports
- Flexeril and Lisinopril: 3,228 reports
- Flexeril and Prilosec: 3,134 reports
Browse all interactions between Flexeril and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Diprivan interactions:
- Diprivan and Fentanyl: 945 reports
- Diprivan and Morphine: 554 reports
- Diprivan and Sevoflurane: 483 reports
- Diprivan and Lasix: 470 reports
- Diprivan and Heparin: 427 reports
- Diprivan and Ultiva: 398 reports
- Diprivan and Versed: 387 reports
- Diprivan and Augmentin: 367 reports
- Diprivan and Tracrium: 342 reports
- Diprivan and Cefazolin: 309 reports
Browse all interactions between Diprivan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on cyclobenzaprine hydrochloride and propofol (the active ingredients of Flexeril and Diprivan, respectively), and Flexeril and Diprivan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Flexeril and Diprivan.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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