Flexeril and Edluar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flexeril (cyclobenzaprine hydrochloride) and Edluar (zolpidem tartrate). Common drug interactions include fatigue among females.

The phase IV clinical study analyzes what interactions people have when they take Flexeril and Edluar. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Flexeril?

Flexeril has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. eHealthMe is studying from 38,308 Flexeril users. Check the latest studies of Flexeril.

What is Edluar?

Edluar has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 157 Edluar users. Check the latest studies of Edluar.

On Jul, 22, 2026

12 people who take Flexeril and Edluar together, and have interactions are studied.

What are the common drug interactions of Flexeril and Edluar, by gender? *:

female:

Fatigue (feeling of tiredness)
Craniocerebral injury (injury to cranium and brain)
Hypoaesthesia (reduced sense of touch or sensation)
Intervertebral disc degeneration (spinal disc degeneration)
Joint injury
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Pain of skin
Rectal haemorrhage (bleeding from anus)
Spinal column injury (spinal cord bone injury)
Therapeutic response unexpected

male:

n/a

What are the common drug interactions of Flexeril and Edluar, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Dyspnoea (difficult or laboured respiration)
Hot flush (sudden feelings of heat)
Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)

30-39:

n/a

40-49:

Craniocerebral injury (injury to cranium and brain)

50-59:

Colitis (inflammation of colon)
Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding)

60+:

n/a

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 10 people, 83.33%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 58.33%
Stress And Anxiety: 1 person, 8.33%
Pain: 1 person, 8.33%
Neuralgia (pain in one or more nerves): 1 person, 8.33%
Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 8.33%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 8.33%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 1 person, 8.33%
Gastritis (inflammation of stomach): 1 person, 8.33%
Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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