Flexeril and Mirabegron drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flexeril (cyclobenzaprine hydrochloride) and Mirabegron (mirabegron). Common drug interactions include fatigue among females.

The phase IV clinical study analyzes what interactions people have when they take Flexeril and Mirabegron. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Flexeril?

Flexeril has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. eHealthMe is studying from 38,308 Flexeril users. Check the latest studies of Flexeril.

What is Mirabegron?

Mirabegron has active ingredients of mirabegron. It is often used in urge incontinence. eHealthMe is studying from 5,414 Mirabegron users. Check the latest studies of Mirabegron.



On Jul, 13, 2026

15 people who take Flexeril and Mirabegron together, and have interactions are studied.

Flexeril and Mirabegron drug interactions.

What are the common drug interactions of Flexeril and Mirabegron, by gender? *:

female:

  1. Fatigue (feeling of tiredness)
  2. Arthralgia (joint pain)
  3. Balance disorder
  4. Bladder dysfunction
  5. Blood pressure immeasurable
  6. Chills (felling of cold)
  7. Depression
  8. Dermatitis diaper (diaper rash is a common form of inflamed skin)
  9. Dizziness
  10. Feeding disorder (when children refuse to eat certain food groups)

male:

n/a

What are the common drug interactions of Flexeril and Mirabegron, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
  2. Joint dislocation (a joint position is changed from normal position)
  3. Pain
  4. Pneumonia
  5. Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
  6. Sepsis (a severe blood infection that can lead to organ failure and death)

50-59:

  1. Fatigue (feeling of tiredness)
  2. Back disorder
  3. Cyst (a closed sac)
  4. Cystitis bacterial (inflammation of the wall of the bladder by bacteria escherichia coli)
  5. Dermal cyst
  6. Diabetes mellitus inadequate control
  7. Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
  8. Gastrointestinal bacterial infection (infection of the stomach and intestines caused by bacteria)
  9. Headache (pain in head)
  10. Hypoacusis (loss of hearing)

60+:

  1. Urinary tract infection
  2. Alopecia (absence of hair from areas of the body)
  3. Dizziness
  4. Fatigue (feeling of tiredness)
  5. Feeding disorder (when children refuse to eat certain food groups)
  6. Feeling hot
  7. Gastrointestinal infection (infection of stomach and intestine)
  8. Hemiparesis (weakness on one side of the body)
  9. Hypersensitivity
  10. Joint stiffness

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 40.00%
  2. Gait Disturbance: 4 people, 26.67%
  3. Wheezing (a high-pitched whistling sound made while you breath): 2 people, 13.33%
  4. Pain: 2 people, 13.33%
  5. Diarrhea: 2 people, 13.33%
  6. Migraine (headache): 2 people, 13.33%
  7. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 13.33%
  8. Pain In Extremity: 1 person, 6.67%
  9. Neuropathy Peripheral (surface nerve damage): 1 person, 6.67%
  10. Restless Leg Syndrome (a powerful urge to move your legs): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Flexeril and Mirabegron?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Flexeril and Mirabegron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Flexeril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Mirabegron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Flexeril and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mirabegron and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on cyclobenzaprine hydrochloride and mirabegron (the active ingredients of Flexeril and Mirabegron, respectively), and Flexeril and Mirabegron (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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