Flexeril and Peginterferon drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flexeril (cyclobenzaprine hydrochloride) and Peginterferon (peginterferon alfa-2a; ribavirin). Common drug interactions include syncope among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Flexeril and Peginterferon. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Flexeril?

Flexeril has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. eHealthMe is studying from 38,308 Flexeril users. Check the latest studies of Flexeril.

What is Peginterferon?

Peginterferon has active ingredients of peginterferon alfa-2a; ribavirin. It is often used in hepatitis c. eHealthMe is studying from 13,778 Peginterferon users. Check the latest studies of Peginterferon.

On Jul, 09, 2026

21 people who take Flexeril and Peginterferon together, and have interactions are studied.

Flexeril and Peginterferon drug interactions.

What are the common drug interactions of Flexeril and Peginterferon, by gender? *:

female:

Syncope (loss of consciousness with an inability to maintain postural tone)
Tremor (trembling or shaking movements in one or more parts of your body)
Abdominal discomfort
Abdominal pain
Anaemia (lack of blood)
Anorectal discomfort
Appetite disorder (abnormal eating habits)
Arthralgia (joint pain)
Blood iron decreased
Blood potassium decreased

male:

Anxiety
Osteopenia (a condition where bone mineral density is lower than normal)
Tooth fracture
Tooth loss
Abscess oral (abscess in the mouth)
Anaemia macrocytic (a macrocytic class of anaemia)
Aortic dilatation
Arteriovenous fistula
Arthralgia (joint pain)
Back disorder

What are the common drug interactions of Flexeril and Peginterferon, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Dizziness
Dyspnoea (difficult or laboured respiration)
Electrolyte imbalance
Escherichia infection (bacterial infection by escherichia coli)
Exostosis (formation of new bone on the surface of a bone)
Fall
Fistula (an abnormal connection or passageway between two)
Glaucoma (increased fluid pressure in the eye with vision loss)
Hepatic steatosis (fatty liver disease)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)

30-39:

Pneumonia
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Dizziness
Injection site pain
Nausea (feeling of having an urge to vomit)
Platelet count decreased
Pruritus (severe itching of the skin)

40-49:

Abdominal discomfort
Anaemia (lack of blood)
Anorectal discomfort
Arthralgia (joint pain)
Blood iron decreased
Blood urine present
Confusional state
Constipation
Decreased appetite
Disturbance in attention

50-59:

Death
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Tooth loss
Fear of falling
Headache (pain in head)
Nephrolithiasis (calculi in the kidneys)
Pain in extremity
Physical disability
Syncope (loss of consciousness with an inability to maintain postural tone)
Abdominal pain

60+:

n/a

What are the existing conditions these people have? *

Hiv Infection: 3 people, 14.29%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 9.52%
Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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