Flexeril and Quinapril drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flexeril (cyclobenzaprine hydrochloride) and Quinapril (quinapril hydrochloride). Common drug interactions include musculoskeletal stiffness among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Flexeril and Quinapril. It is created by eHealthMe based on reports of 76 people who take the same drugs from the FDA, and is updated regularly.

What is Flexeril?

Flexeril has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. eHealthMe is studying from 38,308 Flexeril users. Check the latest studies of Flexeril.

What is Quinapril?

Quinapril has active ingredients of quinapril hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 12,927 Quinapril users. Check the latest studies of Quinapril.

On Aug, 01, 2026

76 people who take Flexeril and Quinapril together, and have interactions are studied.

Flexeril and Quinapril drug interactions.

What are the common drug interactions of Flexeril and Quinapril, by gender? *:

female:

Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Neuropathy peripheral (surface nerve damage)
Night sweats (sweating in night)
Peripheral arterial occlusive disease (reproducible ischemic muscle pain)
Pyrexia (fever)
Rectal haemorrhage (bleeding from anus)
Sunburn
Swelling
Tooth extraction
Type 2 diabetes mellitus

male:

Anxiety
Diarrhoea
Cardiac valve disease (heart valve disease)
Chest pain
Compression fracture (fracture due to pressure caused by injury)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Cough
Decreased appetite
Depression
Emotional distress

What are the common drug interactions of Flexeril and Quinapril, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Breast cancer
Fall
Fatigue (feeling of tiredness)
Malaise (a feeling of general discomfort or uneasiness)
Pain
Vomiting
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)

20-29:

n/a

30-39:

Hypotension (abnormally low blood pressure)

40-49:

Anxiety
Depression
Injury
Pain
Abdominal pain upper
Emotional distress
Psychological trauma
Sexual dysfunction (difficulty experienced by an individual or a couple during any stage of a normal sexual activity)
Sleep disorder
Uterine perforation (accidental puncture of the uterus)

50-59:

Tooth extraction
Type 2 diabetes mellitus
Visual acuity reduced (reduced clearness of vision)
Weight decreased
Colitis (inflammation of colon)
Eye disorder
Myalgia (muscle pain)
Rash
Somnolence (a state of near-sleep, a strong desire for sleep)
Abnormal dreams

60+:

Fall
Pain
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Sedation
Dyspnoea (difficult or laboured respiration)
Bladder disorder
Dementia (madness)
Overdose
Creatinine renal clearance increased
Drug abuse

What are the existing conditions these people have? *

Pain: 26 people, 34.21%
Fibromyalgia (a long-term condition which causes pain all over the body): 23 people, 30.26%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 19 people, 25.00%
Insomnia (sleeplessness): 19 people, 25.00%
Gastric Ulcer (stomach ulcer): 19 people, 25.00%
Thyroid Diseases: 19 people, 25.00%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 18 people, 23.68%
Bladder Disorder: 17 people, 22.37%
Chest Pain: 17 people, 22.37%
Constipation: 17 people, 22.37%

* Approximation only. Some reports may have incomplete information.

Do you take Flexeril and Quinapril?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously