Flexeril and Selenium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flexeril (cyclobenzaprine hydrochloride) and Selenium (selenium). Common drug interactions include abdominal pain among females and neck pain among males.

The phase IV clinical study analyzes what interactions people have when they take Flexeril and Selenium. It is created by eHealthMe based on reports of 80 people who take the same drugs from the FDA, and is updated regularly.

What is Flexeril?

Flexeril has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. eHealthMe is studying from 38,308 Flexeril users. Check the latest studies of Flexeril.

What is Selenium?

Selenium has active ingredients of selenium. It is often used in vitamin supplementation. eHealthMe is studying from 5,314 Selenium users. Check the latest studies of Selenium.



On Jul, 17, 2026

80 people who take Flexeril and Selenium together, and have interactions are studied.

Flexeril and Selenium drug interactions.

What are the common drug interactions of Flexeril and Selenium, by gender? *:

female:

  1. Abdominal pain
  2. Arthralgia (joint pain)
  3. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  4. Asthma
  5. Blood cholesterol increased
  6. Cardiac failure
  7. Cellulitis (infection under the skin)
  8. Chest pain
  9. Constipation
  10. Disorientation (disability in which the senses of time, direction, and recognition of people and places)

male:

  1. Neck pain
  2. Blood pressure increased
  3. Exostosis (formation of new bone on the surface of a bone)
  4. Flatulence (flatus expelled through the anus)
  5. Insomnia (sleeplessness)
  6. Nausea (feeling of having an urge to vomit)
  7. Neuralgia (pain in one or more nerves)
  8. Stress
  9. Therapeutic response unexpected
  10. Vitamin d decreased

What are the common drug interactions of Flexeril and Selenium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Blood pressure increased
  2. Dizziness
  3. Dry eye (lack of adequate tears)
  4. Eye irritation
  5. Eye pain
  6. Fatigue (feeling of tiredness)
  7. Fear
  8. Lethargy (tiredness)
  9. Loss of consciousness
  10. Nasopharyngitis (inflammation of the nasopharynx)

40-49:

  1. Intervertebral disc protrusion (spinal disc protrusion)
  2. Aphthous ulcer (mouth ulcer)
  3. Constipation
  4. Exostosis (formation of new bone on the surface of a bone)
  5. Flatulence (flatus expelled through the anus)
  6. Insomnia (sleeplessness)
  7. Nausea (feeling of having an urge to vomit)
  8. Neck pain
  9. Neuralgia (pain in one or more nerves)
  10. Stress

50-59:

  1. Arthralgia (joint pain)
  2. Depression
  3. Myalgia (muscle pain)
  4. Nausea (feeling of having an urge to vomit)
  5. Acute sinusitis
  6. Alopecia (absence of hair from areas of the body)
  7. Anaemia (lack of blood)
  8. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  9. Arthropathy
  10. Asthma

60+:

  1. Nausea (feeling of having an urge to vomit)
  2. Headache (pain in head)
  3. Hyperhidrosis (abnormally increased sweating)
  4. Renal failure (kidney dysfunction)
  5. Cardiac failure
  6. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  7. Haemoglobin decreased
  8. Activities of daily living impaired
  9. Agitation (state of anxiety or nervous excitement)
  10. Alanine aminotransferase increased

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 42 people, 52.50%
  2. Pain: 20 people, 25.00%
  3. High Blood Pressure: 11 people, 13.75%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 12.50%
  5. Nausea (feeling of having an urge to vomit): 7 people, 8.75%
  6. Multiple Myeloma (cancer of the plasma cells): 6 people, 7.50%
  7. Osteoporosis (bones weak and more likely to break): 5 people, 6.25%
  8. Inflammation: 5 people, 6.25%
  9. Constipation: 5 people, 6.25%
  10. Sinusitis (inflammation of sinus): 4 people, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Flexeril and Selenium?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Flexeril and Selenium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Flexeril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Selenium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Flexeril and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Selenium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on cyclobenzaprine hydrochloride and selenium (the active ingredients of Flexeril and Selenium, respectively), and Flexeril and Selenium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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