Flomax and Avandaryl drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flomax (tamsulosin hydrochloride) and Avandaryl (glimepiride; rosiglitazone maleate). Common drug interactions include pulmonary hypertension among females and coronary artery disease among males.

The phase IV clinical study analyzes what interactions people have when they take Flomax and Avandaryl. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Flomax?

Flomax has active ingredients of tamsulosin hydrochloride. It is often used in enlarged prostate. eHealthMe is studying from 52,865 Flomax users. Check the latest studies of Flomax.

What is Avandaryl?

Avandaryl has active ingredients of glimepiride; rosiglitazone maleate. It is often used in diabetes. eHealthMe is studying from 2,660 Avandaryl users. Check the latest studies of Avandaryl.

On Jul, 27, 2026

24 people who take Flomax and Avandaryl together, and have interactions are studied.

What are the common drug interactions of Flomax and Avandaryl, by gender? *:

female:

Pulmonary hypertension (increase in blood pressure in the lung artery)
Renal failure (kidney dysfunction)
Renal failure acute (rapid kidney dysfunction)
Renal failure chronic (long lasting kidney dysfunction)
Renal injury (kidney injury)
Speech disorder
Chronic kidney disease
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Disturbance in attention
Fatigue (feeling of tiredness)

male:

Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Anxiety
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Blood glucose increased
Cardiac failure congestive
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dyspepsia (indigestion)
Fluid overload (too much fluid in the blood)
Haematocrit decreased
Loss of consciousness

What are the common drug interactions of Flomax and Avandaryl, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anxiety
Cardiac disorder
Cardiovascular disorder (heart diseases)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)

50-59:

Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease)
Crying
Depression
Disturbance in attention
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Fatigue (feeling of tiredness)
Feeling of despair
Insomnia (sleeplessness)
Memory impairment
Speech disorder

60+:

Arrhythmia (irregular heartbeat)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cardiac failure congestive
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dyspepsia (indigestion)
Fluid overload (too much fluid in the blood)
Haematocrit decreased
Loss of consciousness
Malignant hypertension (a hypertensive emergency is a condition in which elevated blood pressure results in target organ damage)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)

What are the existing conditions these people have? *

High Blood Pressure: 5 people, 20.83%
High Blood Cholesterol: 4 people, 16.67%
Depression: 4 people, 16.67%
Weakness: 3 people, 12.50%
Type 2 Diabetes: 3 people, 12.50%
Sleep Disorder: 3 people, 12.50%
Renal Disorder (kidney disease): 3 people, 12.50%
Fluid Imbalance (imbalance of fluid in body in intake and fluid lost): 3 people, 12.50%
Blood Pressure Abnormal: 3 people, 12.50%
Abdominal Discomfort: 3 people, 12.50%

* Approximation only. Some reports may have incomplete information.

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