Florinef and Exidine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Florinef (fludrocortisone acetate) and Exidine (chlorhexidine gluconate). Common drug interactions include deafness among females and anaemia among males.
The phase IV clinical study analyzes what interactions people have when they take Florinef and Exidine. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.
What is Florinef?
Florinef has active ingredients of fludrocortisone acetate. It is often used in addison's disease. eHealthMe is studying from 3,834 Florinef users. Check the latest studies of Florinef.
What is Exidine?
Exidine has active ingredients of chlorhexidine gluconate. eHealthMe is studying from 17,299 Exidine users. Check the latest studies of Exidine.
33 people who take Florinef and Exidine together, and have interactions are studied.

What are the common drug interactions of Florinef and Exidine, by gender? *:
female:
- Deafness
- Deformity (disfigurement)
- Disability
- Dyspnoea (difficult or laboured respiration)
- Dyspnoea exertional (breathlessness or shortness of breath)
- Ear pain
- Gait disturbance
- Gingival disorder (gum disease)
- Infection
- Irritable bowel syndrome
male:
- Anaemia (lack of blood)
- Anxiety
- Headache (pain in head)
- Hepatitis (inflammation of the liver)
- Hot flush (sudden feelings of heat)
- Hypoaesthesia (reduced sense of touch or sensation)
- Injury
- Loss of consciousness
- Migraine (headache)
- Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
What are the common drug interactions of Florinef and Exidine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Pain
- Abdominal discomfort
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Arthralgia (joint pain)
- Back pain
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Dizziness
- Emotional distress
- Fall
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Neuropathy peripheral (surface nerve damage)
- Pain
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Weight decreased
- Adrenal neoplasm (abnormal growth of adrenal gland)
- Anaemia (lack of blood)
- Ankle fracture
- Arthralgia (joint pain)
- Asthenia (weakness)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
60+:
- Anaemia (lack of blood)
- Anxiety
- Headache (pain in head)
- Hepatitis (inflammation of the liver)
- Hot flush (sudden feelings of heat)
- Hypoaesthesia (reduced sense of touch or sensation)
- Injury
- Loss of consciousness
- Migraine (headache)
- Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
What are the existing conditions these people have? *
- Multiple Myeloma (cancer of the plasma cells): 12 people, 36.36%
- Light Chain Analysis Increased: 12 people, 36.36%
- Infection: 5 people, 15.15%
- Neoplasm Malignant (cancer tumour): 3 people, 9.09%
- Osteoporosis (bones weak and more likely to break): 2 people, 6.06%
- Metastases To Prostate (cancer spreads to prostate): 2 people, 6.06%
* Approximation only. Some reports may have incomplete information.
Do you take Florinef and Exidine?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Florinef and Exidine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Florinef:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Exidine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Florinef and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Exidine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on fludrocortisone acetate and chlorhexidine gluconate (the active ingredients of Florinef and Exidine, respectively), and Florinef and Exidine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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