Florinef and Lorazepam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Florinef (fludrocortisone acetate) and Lorazepam (lorazepam). Common drug interactions include abdominal pain among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Florinef and Lorazepam. It is created by eHealthMe based on reports of 83 people who take the same drugs from the FDA, and is updated regularly.

What is Florinef?

Florinef has active ingredients of fludrocortisone acetate. It is often used in addison's disease. eHealthMe is studying from 3,834 Florinef users. Check the latest studies of Florinef.

What is Lorazepam?

Lorazepam has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 165,639 Lorazepam users. Check the latest studies of Lorazepam.

On Jul, 10, 2026

83 people who take Florinef and Lorazepam together, and have interactions are studied.

Florinef and Lorazepam drug interactions.

What are the common drug interactions of Florinef and Lorazepam, by gender? *:

female:

Abdominal pain
Atelectasis (partial or complete collapse of the lung)
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Carotid artery stenosis (narrowing of carotid artery)
Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
Constipation
Depression
Dizziness
Failure to thrive (inadequate weight gain and physical growth in children)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

male:

Pneumonia
Asthenia (weakness)
Cough
Decreased appetite
Disease progression
Dyspnoea (difficult or laboured respiration)
Malaise (a feeling of general discomfort or uneasiness)
Vomiting
Weight increased
Ageusia (loss of taste functions of the tongue)

What are the common drug interactions of Florinef and Lorazepam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Tolerance increased

40-49:

Nausea (feeling of having an urge to vomit)
Vomiting
Pancreatitis (inflammation of pancreas)
Chills (felling of cold)
Diarrhoea
Faecal incontinence (a lack of control over passing stool)
Fatigue (feeling of tiredness)
Hyperhidrosis (abnormally increased sweating)
Malaise (a feeling of general discomfort or uneasiness)
Somnolence (a state of near-sleep, a strong desire for sleep)

50-59:

Decreased appetite
Depression
Diarrhoea
Disease progression
Dysgeusia (disorder of the sense of taste)
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Fungal infection
Gout (uric acid crystals building up in the body)
Hair colour changes

60+:

Dehydration (dryness resulting from the removal of water)
Asthenia (weakness)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Depression
Blood creatinine increased
Constipation
Dizziness
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Pain in extremity
Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 11 people, 13.25%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 9 people, 10.84%
Depression: 7 people, 8.43%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 7 people, 8.43%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 7.23%
Pain: 5 people, 6.02%
Nausea (feeling of having an urge to vomit): 5 people, 6.02%
Insomnia (sleeplessness): 5 people, 6.02%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 6.02%
High Blood Pressure: 5 people, 6.02%

* Approximation only. Some reports may have incomplete information.

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