Florinef and Rocephin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Florinef (fludrocortisone acetate) and Rocephin (ceftriaxone sodium). Common drug interactions include cardiac arrest among females and atrial fibrillation among males.

The phase IV clinical study analyzes what interactions people have when they take Florinef and Rocephin. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Florinef?

Florinef has active ingredients of fludrocortisone acetate. It is often used in addison's disease. eHealthMe is studying from 3,834 Florinef users. Check the latest studies of Florinef.

What is Rocephin?

Rocephin has active ingredients of ceftriaxone sodium. It is often used in infection. eHealthMe is studying from 15,665 Rocephin users. Check the latest studies of Rocephin.

On Jul, 11, 2026

15 people who take Florinef and Rocephin together, and have interactions are studied.

Florinef and Rocephin drug interactions.

What are the common drug interactions of Florinef and Rocephin, by gender? *:

female:

Cardiac arrest
Dehydration (dryness resulting from the removal of water)
Device related infection
Haematoma (collection of blood outside the blood vessels)
Haemorrhage (bleeding)
Acute respiratory distress syndrome
Acute respiratory failure
Adenocarcinoma pancreas (cancer of pancreas)
Alanine aminotransferase increased
Apnoea (suspension of external breathing)

male:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Hypokalaemia (low potassium)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Neuropathy peripheral (surface nerve damage)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Plasma cell myeloma (cancer that begins in plasma cells)
Platelet count decreased
Renal impairment (severely reduced kidney function)
Sepsis (a severe blood infection that can lead to organ failure and death)

What are the common drug interactions of Florinef and Rocephin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Alanine aminotransferase increased
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)

40-49:

n/a

50-59:

Encephalopathy (functioning of the brain is affected by some agent or condition)
Cardiac arrest
Thermal burn (burn by heat)
Adenocarcinoma pancreas (cancer of pancreas)
Respiratory failure (inadequate gas exchange by the respiratory system)

60+:

Dehydration (dryness resulting from the removal of water)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Herpes zoster
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Neuropathy peripheral (surface nerve damage)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Plasma cell myeloma (cancer that begins in plasma cells)
Platelet count decreased
Renal impairment (severely reduced kidney function)
Somnolence (a state of near-sleep, a strong desire for sleep)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 5 people, 33.33%
Urinary Tract Infection: 2 people, 13.33%
Sepsis (a severe blood infection that can lead to organ failure and death): 2 people, 13.33%
Pain: 2 people, 13.33%
Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 2 people, 13.33%
Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 2 people, 13.33%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 2 people, 13.33%
Erythema Multiforme (a type of hypersensitivity reaction): 2 people, 13.33%
Cough: 2 people, 13.33%
Constipation: 2 people, 13.33%

* Approximation only. Some reports may have incomplete information.

Do you take Florinef and Rocephin?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously