Flovent hfa and Prolia drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flovent hfa (fluticasone propionate) and Prolia (denosumab). Common drug interactions include therapeutic response unexpected among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Flovent hfa and Prolia. It is created by eHealthMe based on reports of 52 people who take the same drugs from the FDA, and is updated regularly.

What is Flovent hfa?

Flovent hfa has active ingredients of fluticasone propionate. It is often used in asthma. eHealthMe is studying from 7,457 Flovent hfa users. Check the latest studies of Flovent hfa.

What is Prolia?

Prolia has active ingredients of denosumab. It is often used in osteoporosis. eHealthMe is studying from 151,388 Prolia users. Check the latest studies of Prolia.

On Jul, 07, 2026

52 people who take Flovent hfa and Prolia together, and have interactions are studied.

Flovent hfa and Prolia drug interactions.

What are the common drug interactions of Flovent Hfa and Prolia, by gender? *:

female:

Therapeutic response unexpected
Vascular injury
Acute respiratory failure
Adverse drug reaction
Nausea (feeling of having an urge to vomit)
Drug intolerance (drug sensitivity)
Fatigue (feeling of tiredness)
Pain
Headache (pain in head)
Migraine (headache)

male:

Arthralgia (joint pain)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Rash
Spinal fracture (fracture in one of vertebrae)
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Fatigue (feeling of tiredness)
Joint range of motion decreased (disease of joint movement)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Dysphonia (speech disorder attributable to a disorder of phonation)
Fall

What are the common drug interactions of Flovent Hfa and Prolia, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Blood calcium increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Dyspnoea (difficult or laboured respiration)
Heart rate irregular
Immune system disorder
Respiratory tract infection
Sinusitis (inflammation of sinus)

50-59:

Hand deformity
Hyperhidrosis (abnormally increased sweating)
Interstitial lung disease
Multiple fractures
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Myopathy (a muscular disease in which the muscle fibres do not function)
Nausea (feeling of having an urge to vomit)
Osteonecrosis (death of bone)
Pain
Pneumonia

60+:

Nausea (feeling of having an urge to vomit)
Headache (pain in head)
Malaise (a feeling of general discomfort or uneasiness)
Vision blurred
Peripheral swelling
Rash
Alopecia (absence of hair from areas of the body)
Anxiety
Aortic arteriosclerosis (hardening of the aortic arteries)
Blindness

What are the existing conditions these people have? *

Sleep Disorder: 8 people, 15.38%
Pain: 6 people, 11.54%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 7.69%
Cough: 4 people, 7.69%
Wheezing (a high-pitched whistling sound made while you breath): 3 people, 5.77%
Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 3 people, 5.77%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 5.77%
Muscle Spasms (muscle contraction): 3 people, 5.77%
Immune System Disorder: 3 people, 5.77%
Dyspnea (difficult or laboured breathing): 3 people, 5.77%

* Approximation only. Some reports may have incomplete information.

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