Flovent hfa and Xopenex hfa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flovent hfa (fluticasone propionate) and Xopenex hfa (levalbuterol tartrate). Common drug interactions include bacterial infection among females and dysgeusia among males.

The phase IV clinical study analyzes what interactions people have when they take Flovent hfa and Xopenex hfa. It is created by eHealthMe based on reports of 68 people who take the same drugs from the FDA, and is updated regularly.

What is Flovent hfa?

Flovent hfa has active ingredients of fluticasone propionate. It is often used in asthma. eHealthMe is studying from 7,457 Flovent hfa users. Check the latest studies of Flovent hfa.

What is Xopenex hfa?

Xopenex hfa has active ingredients of levalbuterol tartrate. It is often used in asthma. eHealthMe is studying from 2,529 Xopenex hfa users. Check the latest studies of Xopenex hfa.



On Jul, 15, 2026

68 people who take Flovent hfa and Xopenex hfa together, and have interactions are studied.

Flovent hfa and Xopenex hfa drug interactions.

What are the common drug interactions of Flovent Hfa and Xopenex Hfa, by gender? *:

female:

  1. Bacterial infection
  2. Blood magnesium increased
  3. Cellulitis (infection under the skin)
  4. Contusion (a type of hematoma of tissue in which capillaries)
  5. Dehydration (dryness resulting from the removal of water)
  6. Diarrhoea
  7. Drug hypersensitivity
  8. Ear pain
  9. Frequent bowel movements
  10. Herpes zoster

male:

  1. Dysgeusia (disorder of the sense of taste)
  2. Dyspnoea (difficult or laboured respiration)
  3. Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
  4. Leukocytosis (increased white blood cells)
  5. Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
  6. Pneumonia
  7. Anxiety
  8. Coma (state of unconsciousness lasting more than six hours)
  9. Death
  10. Fall

What are the common drug interactions of Flovent Hfa and Xopenex Hfa, by age (0-1 to 60+)? *:

0-1:

  1. Respiratory syncytial virus test positive

2-9:

  1. Aphasia (damage to the parts of the brain that control language)
  2. Confusional state
  3. Granulocytopenia (lack of granulocyte)
  4. Neutrophil percentage decreased

10-19:

  1. Abnormal behaviour
  2. Cardiac failure
  3. Crying
  4. Depression
  5. Fluid overload (too much fluid in the blood)
  6. Hospitalisation
  7. Malaise (a feeling of general discomfort or uneasiness)
  8. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  9. Oedema peripheral (superficial swelling)
  10. Oropharyngeal pain

20-29:

n/a

30-39:

  1. Back pain
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness)
  3. Choking (mechanical obstruction of the flow of air from the environment into the lungs)
  4. Cystatin c increased
  5. Cystic fibrosis (disease of the secretary glands)
  6. Dark circles under eyes
  7. Death
  8. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  9. Drug ineffective
  10. Dry eye (lack of adequate tears)

40-49:

  1. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  2. Cardiovascular disorder (heart diseases)
  3. Dyspnoea (difficult or laboured respiration)
  4. Ear infection

50-59:

  1. Immunodeficiency
  2. Influenza
  3. Insomnia (sleeplessness)
  4. Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  5. Muscle spasticity (tight or stiff muscles and an inability to control those muscles)
  6. Nausea (feeling of having an urge to vomit)
  7. Pain
  8. Palpitations (feelings or sensations that your heart is pounding or racing)
  9. Periorbital cellulitis (inflammation and infection of the eyelid and the skin surrounding the eye)
  10. Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)

60+:

  1. Dyspnoea (difficult or laboured respiration)
  2. Vocal cord disorder
  3. Glycosylated haemoglobin increased
  4. Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
  5. Leukocytosis (increased white blood cells)
  6. Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
  7. Muscle spasms (muscle contraction)
  8. Urinary tract infection
  9. Asthenia (weakness)
  10. Coma (state of unconsciousness lasting more than six hours)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 12 people, 17.65%
  2. Immunodeficiency Common Variable: 10 people, 14.71%
  3. Immunodeficiency: 10 people, 14.71%
  4. Multiple Myeloma (cancer of the plasma cells): 4 people, 5.88%
  5. Dyspnea (difficult or laboured breathing): 4 people, 5.88%
  6. Diabetes: 4 people, 5.88%
  7. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Flovent hfa and Xopenex hfa:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Flovent hfa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Xopenex hfa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Flovent hfa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Xopenex hfa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on fluticasone propionate and levalbuterol tartrate (the active ingredients of Flovent hfa and Xopenex hfa, respectively), and Flovent hfa and Xopenex hfa (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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