Flovent and Plendil drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Flovent (fluticasone propionate) and Plendil (felodipine). Common drug interactions include cardiac murmur among females and dyspnoea among males.
The phase IV clinical study analyzes what interactions people have when they take Flovent and Plendil. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.
What is Flovent?
Flovent has active ingredients of fluticasone propionate. It is often used in asthma. eHealthMe is studying from 44,817 Flovent users. Check the latest studies of Flovent.
What is Plendil?
Plendil has active ingredients of felodipine. It is often used in high blood pressure. eHealthMe is studying from 4,990 Plendil users. Check the latest studies of Plendil.
26 people who take Flovent and Plendil together, and have interactions are studied.

What are the common drug interactions of Flovent and Plendil, by gender? *:
female:
- Cardiac murmur (an heart sound in valve abnormality)
- Cardiac failure congestive
- Fluid overload (too much fluid in the blood)
- Fluid retention (an abnormal accumulation of fluid in the blood)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Heart injury
- Hepatic failure (liver failure)
- Hepatocellular damage (liver damage)
- Sinus bradycardia (an unusually slow heartbeat due to heart disease)
- Anxiety
male:
- Dyspnoea (difficult or laboured respiration)
- Blood pressure systolic increased
- Osteonecrosis (death of bone)
- Periodontal disease (disease that attacks the gum and bone and around the teeth)
- Renal failure (kidney dysfunction)
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Cough
- Dry mouth
- Haemorrhagic diathesis (bleeding tendency)
- Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
What are the common drug interactions of Flovent and Plendil, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Anxiety
- Cardiac murmur (an heart sound in valve abnormality)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Lacunar infarction (a type of stroke)
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
- Depression
60+:
- Hepatic failure (liver failure)
- Cardiac failure congestive
- Cough
- Disease progression
- Dry mouth
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
- Gingival bleeding (bleeding gums)
- Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
What are the existing conditions these people have? *
- Pain: 4 people, 15.38%
- Carpal Tunnel Syndrome (nerve compression at wrist results numbness weakness, pain , swelling): 3 people, 11.54%
- Back Pain: 3 people, 11.54%
- Type 2 Diabetes: 2 people, 7.69%
- Polymyalgia (pain in many muscles): 2 people, 7.69%
- Itching: 2 people, 7.69%
- Idiopathic Pulmonary Fibrosis (chronic lung disease): 2 people, 7.69%
- Hypersensitivity: 2 people, 7.69%
- Hyperaldosteronism: 2 people, 7.69%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 7.69%
* Approximation only. Some reports may have incomplete information.
Do you take Flovent and Plendil?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Flovent and Plendil:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Flovent:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Plendil:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Flovent and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Plendil and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Lehrer, S., & Rheinstein, P. H. , "Alzheimer’s Disease and Intranasal Fluticasone Propionate in the FDA MedWatch Adverse Events Database", Journal of Alzheimer's disease reports, (Preprint), 1-5., 2018 Jan .
- Lehrer, S., & Rheinstein, P. H. , "Alzheimer’s Disease and Intranasal Fluticasone Propionate in the FDA MedWatch Adverse Events Database", Journal of Alzheimer's disease reports, (Preprint), 1-5., 2018 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on fluticasone propionate and felodipine (the active ingredients of Flovent and Plendil, respectively), and Flovent and Plendil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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