Floxin and Neurontin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Floxin (ofloxacin) and Neurontin (gabapentin). Common drug interactions include chills among females and chest pain among males.

The phase IV clinical study analyzes what interactions people have when they take Floxin and Neurontin. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.

What is Floxin?

Floxin has active ingredients of ofloxacin. eHealthMe is studying from 1,737 Floxin users. Check the latest studies of Floxin.

What is Neurontin?

Neurontin has active ingredients of gabapentin. It is often used in neuralgia. eHealthMe is studying from 107,468 Neurontin users. Check the latest studies of Neurontin.



On Jul, 04, 2026

50 people who take Floxin and Neurontin together, and have interactions are studied.

Floxin and Neurontin drug interactions.

What are the common drug interactions of Floxin and Neurontin, by gender? *:

female:

  1. Chills (felling of cold)
  2. Discomfort
  3. Emotional distress
  4. Fatigue (feeling of tiredness)
  5. Pain in extremity
  6. Pneumonia
  7. Sepsis (a severe blood infection that can lead to organ failure and death)
  8. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  9. Dyspnoea (difficult or laboured respiration)
  10. Injury

male:

  1. Chest pain
  2. Cough
  3. Blood urea increased
  4. Cardiac failure congestive
  5. Cerebral atrophy (decrement in size of brain)
  6. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  7. Colitis (inflammation of colon)
  8. Constipation
  9. Electrocardiogram st-t change
  10. Fall

What are the common drug interactions of Floxin and Neurontin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Anxiety
  2. Back pain
  3. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  4. Cough
  5. Depression
  6. Dyspnoea (difficult or laboured respiration)
  7. Fatigue (feeling of tiredness)
  8. Oxygen saturation decreased
  9. Upper respiratory tract infection
  10. Wheezing (a high-pitched whistling sound made while you breath)

40-49:

  1. Anxiety
  2. Depression
  3. Dizziness
  4. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  5. Hyperhidrosis (abnormally increased sweating)
  6. Insomnia (sleeplessness)
  7. Nausea (feeling of having an urge to vomit)
  8. Urinary tract infection
  9. Abdominal distension
  10. Asthenia (weakness)

50-59:

  1. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  2. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  3. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  4. Fall
  5. Femoral artery occlusion (obstruction in artery of femur)
  6. Groin infection (infection in groin)
  7. Hypotension (abnormally low blood pressure)
  8. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  9. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  10. Night sweats (sweating in night)

60+:

  1. Drug hypersensitivity
  2. Pneumonia
  3. Blood urea increased
  4. Cardiac failure congestive
  5. Cerebral atrophy (decrement in size of brain)
  6. Chest pain
  7. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  8. Colitis (inflammation of colon)
  9. Cough
  10. Dehydration (dryness resulting from the removal of water)

What are the existing conditions these people have? *

  1. Pain: 5 people, 10.00%
  2. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 4 people, 8.00%

* Approximation only. Some reports may have incomplete information.

Do you take Floxin and Neurontin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Floxin and Neurontin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Floxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Neurontin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Floxin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Neurontin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ofloxacin and gabapentin (the active ingredients of Floxin and Neurontin, respectively), and Floxin and Neurontin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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