Floxin and Wellbutrin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Floxin (ofloxacin) and Wellbutrin (bupropion hydrochloride). Common drug interactions include dyspepsia among females and neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Floxin and Wellbutrin. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Floxin?

Floxin has active ingredients of ofloxacin. eHealthMe is studying from 1,737 Floxin users. Check the latest studies of Floxin.

What is Wellbutrin?

Wellbutrin has active ingredients of bupropion hydrochloride. It is often used in depression. eHealthMe is studying from 117,107 Wellbutrin users. Check the latest studies of Wellbutrin.



On Jul, 10, 2026

25 people who take Floxin and Wellbutrin together, and have interactions are studied.

Floxin and Wellbutrin drug interactions.

What are the common drug interactions of Floxin and Wellbutrin, by gender? *:

female:

  1. Dyspepsia (indigestion)
  2. Dysphagia (a condition in which swallowing is difficult or painful)
  3. Ear infection
  4. Ear pain
  5. Emotional distress
  6. Eructation (release of gas from the digestive tract)
  7. Erythema (redness of the skin)
  8. Eustachian tube dysfunction (eustachian tube problems like clearing the ears when flying, suffering infection, and recurring ear infection)
  9. Excessive eye blinking (excessive blinking is dry eyes)
  10. Extrapyramidal disorder (involuntary muscle spasms in the face and neck)

male:

  1. Neutropenia (an abnormally low number of neutrophils)
  2. Cystitis (inflammation of the wall of the bladder)
  3. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  4. Diabetes mellitus inadequate control
  5. Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
  6. Dysuria (painful or difficult urination)
  7. Haematuria present (presence of blood in urine due to trauma)
  8. Hallucination (an experience involving the perception of something not present)
  9. Hyperglycaemia (high blood sugar)
  10. Inappropriate adh secretion

What are the common drug interactions of Floxin and Wellbutrin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Neutropenia (an abnormally low number of neutrophils)
  2. Cystitis (inflammation of the wall of the bladder)
  3. Cystitis interstitial (unknown cause characterized by bladder pain)
  4. Cystitis ulcerative (inflammation of the wall of the bladder with ulcer)
  5. Night sweats (sweating in night)
  6. Overdose
  7. Ulcer

40-49:

  1. Pain
  2. Abdominal discomfort
  3. Abdominal distension
  4. Acute myocardial infarction (acute heart attack)
  5. Adverse event
  6. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  7. Asthenia (weakness)
  8. Atherosclerosis (disorder of the arteries)
  9. Back pain
  10. Breast cancer female

50-59:

  1. Diabetes mellitus inadequate control
  2. Diabetic coma
  3. Diabetic complication
  4. Hyperlipidaemia (presence of excess lipids in the blood)
  5. Inappropriate adh secretion
  6. Obesity (having too much body fat)
  7. Renal failure (kidney dysfunction)
  8. Type 2 diabetes mellitus
  9. Blood cholesterol increased
  10. Chest pain

60+:

  1. Chronic kidney disease
  2. Drug hypersensitivity
  3. Hyperkalaemia (damage to or disease of the kidney)
  4. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  5. Nausea (feeling of having an urge to vomit)
  6. Nephrogenic anaemia (anaemia due to kidney disease)
  7. Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

  1. Hiv Infection: 13 people, 52.00%
  2. Cystitis Ulcerative (inflammation of the wall of the bladder with ulcer): 13 people, 52.00%
  3. Urinary Tract Infection: 11 people, 44.00%
  4. Prostatitis (inflammation of the prostate gland): 9 people, 36.00%
  5. Pain: 9 people, 36.00%
  6. Gastric Ulcer (stomach ulcer): 6 people, 24.00%
  7. Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 3 people, 12.00%
  8. Night Sweats (sweating in night): 3 people, 12.00%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 12.00%
  10. Fistula (an abnormal connection or passageway between two): 3 people, 12.00%

* Approximation only. Some reports may have incomplete information.

Do you take Floxin and Wellbutrin?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Floxin and Wellbutrin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Floxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Wellbutrin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Floxin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Wellbutrin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ofloxacin and bupropion hydrochloride (the active ingredients of Floxin and Wellbutrin, respectively), and Floxin and Wellbutrin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: