Floxin and Zometa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Floxin (ofloxacin) and Zometa (zoledronic acid). Common drug interactions include pneumonia among females and cholelithiasis among males.

The phase IV clinical study analyzes what interactions people have when they take Floxin and Zometa. It is created by eHealthMe based on reports of 43 people who take the same drugs from the FDA, and is updated regularly.

What is Floxin?

Floxin has active ingredients of ofloxacin. eHealthMe is studying from 1,737 Floxin users. Check the latest studies of Floxin.

What is Zometa?

Zometa has active ingredients of zoledronic acid. It is often used in multiple myeloma. eHealthMe is studying from 71,434 Zometa users. Check the latest studies of Zometa.

On Jul, 11, 2026

43 people who take Floxin and Zometa together, and have interactions are studied.

What are the common drug interactions of Floxin and Zometa, by gender? *:

female:

Pneumonia
Metastases to spine (cancer spreads to spine)
Osteonecrosis of jaw (death of bone of jaw)
Pain in extremity
Foot fracture
Infection
Oedema peripheral (superficial swelling)
Osteonecrosis (death of bone)
Abdominal pain upper
Bone disorder

male:

Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Headache (pain in head)
Chest pain
Dental caries
Emotional distress
Exostosis (formation of new bone on the surface of a bone)
Fistula discharge (discharge from abnormal passage of structure/organ)
Haemangioma (noncancerous, abnormally dense collections of dilated small blood vessels that may occur in the skin or internal organs)
Hepatomegaly (abnormal enlargement of the liver)
Induration (thickening of tissue)

What are the common drug interactions of Floxin and Zometa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal pain upper
Acute respiratory distress syndrome
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anisocytosis (patient's red blood cells are of unequal size)
Anxiety
Asthenia (weakness)
Back pain
Beta 2 microglobulin increased
Blood calcium decreased
Blood glucose increased

40-49:

Alopecia (absence of hair from areas of the body)
Altered state of consciousness (altered state of mind)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anisocytosis (patient's red blood cells are of unequal size)
Anxiety
Aortic arteriosclerosis (hardening of the aortic arteries)
Aortic disorder
Appetite disorder (abnormal eating habits)
Arthralgia (joint pain)
Arthropathy

50-59:

n/a

60+:

Anxiety
Dental caries
Infection
Atelectasis (partial or complete collapse of the lung)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Headache (pain in head)
Abdominal pain upper
Anaemia (lack of blood)
Bone disorder
Bone fragmentation

What are the existing conditions these people have? *

Trismus (reduced opening of the jaws): 18 people, 41.86%
Haemorrhoids (a swollen vein or group of veins in the region of the anus): 5 people, 11.63%
Constipation: 5 people, 11.63%

* Approximation only. Some reports may have incomplete information.

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