Fludara and Crestor drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Fludara (fludarabine phosphate) and Crestor (rosuvastatin calcium). Common drug interactions include full blood count decreased among females and pyrexia among males.
The phase IV clinical study analyzes what interactions people have when they take Fludara and Crestor. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.
What is Fludara?
Fludara has active ingredients of fludarabine phosphate. eHealthMe is studying from 46,686 Fludara users. Check the latest studies of Fludara.
What is Crestor?
Crestor has active ingredients of rosuvastatin calcium. It is often used in high blood cholesterol. eHealthMe is studying from 149,761 Crestor users. Check the latest studies of Crestor.
47 people who take Fludara and Crestor together, and have interactions are studied.

What are the common drug interactions of Fludara and Crestor, by gender? *:
female:
- Full blood count decreased
- Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
- Hypervolaemia (abnormally increased volume of blood)
- Hypotension (abnormally low blood pressure)
- Hypoxia (low oxygen in tissues)
- Necrosis (the death of body tissue)
- Pyrexia (fever)
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Wound
- Nausea (feeling of having an urge to vomit)
male:
- Pyrexia (fever)
- Nausea (feeling of having an urge to vomit)
- Acute graft versus host disease (acute complication following an allogeneic tissue/blood transplant)
- Anaemia (lack of blood)
- Back pain
- Platelet count decreased
- Urinary tract infection
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
What are the common drug interactions of Fludara and Crestor, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Chest pain
- Haemoglobin decreased
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
- Vomiting
- Acute graft versus host disease (acute complication following an allogeneic tissue/blood transplant)
- Alanine aminotransferase increased
- Aspartate aminotransferase increased
- Bacterial infection
- Blood amylase increased
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Abdominal pain upper
- Cardiac failure acute
- Cardiac failure congestive
- Drug ineffective
- Nausea (feeling of having an urge to vomit)
- Nephrolithiasis (calculi in the kidneys)
- Weight decreased
50-59:
- Wound
- Acute graft versus host disease (acute complication following an allogeneic tissue/blood transplant)
- Cytomegalovirus test positive
- Multi-organ failure (multisystem organ failure)
- Renal neoplasm (kidney tumour)
- Venoocclusive disease (small veins in the liver are obstructed)
- Malignant neoplasm progression (cancer tumour came back)
- Cataract (clouding of the lens inside the eye)
- Full blood count decreased
- Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
60+:
- Pyrexia (fever)
- Nausea (feeling of having an urge to vomit)
- Anaemia (lack of blood)
- Back pain
- Platelet count decreased
- Urinary tract infection
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
- Fatigue (feeling of tiredness)
- Rash
What are the existing conditions these people have? *
- Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 22 people, 46.81%
- Type 2 Diabetes: 7 people, 14.89%
- Hyperlipidaemia (presence of excess lipids in the blood): 6 people, 12.77%
- Bone Marrow Conditioning Regimen: 6 people, 12.77%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 10.64%
- Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 4 people, 8.51%
- Infection: 4 people, 8.51%
- High Blood Pressure: 4 people, 8.51%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 8.51%
- Neoplasm Malignant (cancer tumour): 3 people, 6.38%
* Approximation only. Some reports may have incomplete information.
Do you take Fludara and Crestor?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Fludara and Crestor:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Fludara:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Crestor:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Fludara and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Crestor and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on fludarabine phosphate and rosuvastatin calcium (the active ingredients of Fludara and Crestor, respectively), and Fludara and Crestor (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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