Fludarabine phosphate and Lenalidomide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fludarabine phosphate (fludarabine phosphate) and Lenalidomide (lenalidomide). Common drug interactions include febrile neutropenia among females and thrombocytopenia among males.

The phase IV clinical study analyzes what interactions people have when they take Fludarabine phosphate and Lenalidomide. It is created by eHealthMe based on reports of 62 people who take the same drugs from the FDA, and is updated regularly.

What is Fludarabine phosphate?

Fludarabine phosphate has active ingredients of fludarabine phosphate. eHealthMe is studying from 12,840 Fludarabine phosphate users. Check the latest studies of Fludarabine phosphate.

What is Lenalidomide?

Lenalidomide has active ingredients of lenalidomide. eHealthMe is studying from 52,881 Lenalidomide users. Check the latest studies of Lenalidomide.



On Aug, 04, 2026

62 people who take Fludarabine phosphate and Lenalidomide together, and have interactions are studied.

Fludarabine phosphate and Lenalidomide drug interactions.

What are the common drug interactions of Fludarabine Phosphate and Lenalidomide, by gender? *:

female:

  1. Febrile neutropenia (fever with reduced white blood cells)
  2. Graft versus host disease in skin (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the skin)
  3. Liver disorder (liver diseases)
  4. Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles)
  5. Nausea (feeling of having an urge to vomit)
  6. Oedema peripheral (superficial swelling)
  7. Periorbital oedema (swelling around the eyes)
  8. Plasma cell myeloma (cancer that begins in plasma cells)
  9. Second primary malignancy (after getting cure a cancer, a new cancer development)
  10. Spinal compression fracture (fracture due to spinal compression on bone)

male:

  1. Thrombocytopenia (decrease of platelets in blood)
  2. Infection
  3. Lhermitte's sign (an electrical sensation that runs down the back and into the limbs)
  4. Pneumonia
  5. Stem cell transplant
  6. Dehydration (dryness resulting from the removal of water)
  7. Disease progression
  8. Febrile neutropenia (fever with reduced white blood cells)
  9. Pyrexia (fever)
  10. White blood cell count decreased

What are the common drug interactions of Fludarabine Phosphate and Lenalidomide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Lymphopenia (an abnormally low level of lymphocytes in the blood)

40-49:

  1. Disease progression
  2. Drug ineffective
  3. Febrile neutropenia (fever with reduced white blood cells)
  4. Gastric disorder (disease of stomach)
  5. Graft versus host disease in skin (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the skin)
  6. Liver disorder (liver diseases)
  7. Mantle cell lymphoma (cancer of lymphocytes, a type of white blood cell)
  8. Nausea (feeling of having an urge to vomit)
  9. Neoplasm recurrence (reoccurrence of tumour)
  10. Plasma cell myeloma (cancer that begins in plasma cells)

50-59:

  1. Demyelination (loss of the myelin covering of some nerve fibres resulting in their impaired function)
  2. Drug ineffective
  3. Erectile dysfunction
  4. Lhermitte's sign (an electrical sensation that runs down the back and into the limbs)
  5. Thrombocytopenia (decrease of platelets in blood)
  6. Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
  7. Cystitis haemorrhagic (blood in the urine and painful voiding)
  8. Myelosuppression (a decrease in the production of blood cells)
  9. Pneumonia
  10. Polyomavirus-associated nephropathy (polyomavirus-associated kidney disease)

60+:

  1. Thrombocytopenia (decrease of platelets in blood)
  2. Infection
  3. General physical health deterioration (weak health status)
  4. Leukopenia (less number of white blood cells in blood)
  5. Ascites (accumulation of fluid in the abdominal cavity)
  6. Aspergillosis (an infection caused by a fungus called aspergillus)
  7. Atelectasis (partial or complete collapse of the lung)
  8. Bk virus infection
  9. Blood lactate dehydrogenase increased
  10. Clostridial infection (infectious conditions by clostridium bacteria)

What are the existing conditions these people have? *

  1. Parkinson's Disease: 20 people, 32.26%
  2. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 14 people, 22.58%
  3. Multiple Myeloma (cancer of the plasma cells): 7 people, 11.29%
  4. Bone Marrow Conditioning Regimen: 7 people, 11.29%
  5. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 6 people, 9.68%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Fludarabine phosphate and Lenalidomide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Fludarabine phosphate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lenalidomide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Fludarabine phosphate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lenalidomide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on fludarabine phosphate and lenalidomide (the active ingredients of Fludarabine phosphate and Lenalidomide, respectively), and Fludarabine phosphate and Lenalidomide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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