Fludarabine phosphate and Vancomycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fludarabine phosphate (fludarabine phosphate) and Vancomycin (vancomycin). Common drug interactions include mean cell haemoglobin concentration decreased among females and tubulointerstitial nephritis among males.

The phase IV clinical study analyzes what interactions people have when they take Fludarabine phosphate and Vancomycin. It is created by eHealthMe based on reports of 71 people who take the same drugs from the FDA, and is updated regularly.

What is Fludarabine phosphate?

Fludarabine phosphate has active ingredients of fludarabine phosphate. eHealthMe is studying from 12,840 Fludarabine phosphate users. Check the latest studies of Fludarabine phosphate.

What is Vancomycin?

Vancomycin has active ingredients of vancomycin. eHealthMe is studying from 17,165 Vancomycin users. Check the latest studies of Vancomycin.

On Jul, 11, 2026

71 people who take Fludarabine phosphate and Vancomycin together, and have interactions are studied.

Fludarabine phosphate and Vancomycin drug interactions.

What are the common drug interactions of Fludarabine Phosphate and Vancomycin, by gender? *:

female:

Mean cell haemoglobin concentration decreased (less concentration of haemoglobin in a given volume of packed red blood cells)
Mean cell haemoglobin decreased (less than normal haemoglobin per red blood cell in a sample of blood)
Mean cell volume decreased (less of the average red blood cell volume)
Monocyte count decreased
Red blood cell count decreased
Red blood cells urine positive
Red cell distribution width increased
Reticulocyte count decreased
T-lymphocyte count decreased
T-lymphocyte count increased

male:

Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
Pyrexia (fever)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Febrile neutropenia (fever with reduced white blood cells)
White blood cell count decreased
Anaemia (lack of blood)
Thrombocytopenia (decrease of platelets in blood)
Cytomegalovirus infection

What are the common drug interactions of Fludarabine Phosphate and Vancomycin, by age (0-1 to 60+)? *:

0-1:

Disease progression
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Stenotrophomonas infection
White blood cell count decreased
Atrophy (wasting away of a part of the body)
Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
Focal segmental glomerulosclerosis (scar tissue that forms in parts of the kidney called glomeruli)
Mesangioproliferative glomerulonephritis (an inflammatory disease of both kidneys)

2-9:

Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Mesangioproliferative glomerulonephritis (an inflammatory disease of both kidneys)
Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
Focal segmental glomerulosclerosis (scar tissue that forms in parts of the kidney called glomeruli)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Restrictive cardiomyopathy (a condition in which the walls of the lower chambers of the heart (the ventricles) are abnormally rigid and lack the flexibility)
Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)
Heart transplant
Mucosal inflammation (infection of mucous membrane)

10-19:

Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
Bk virus infection
Brain abscess
Cerebral toxoplasmosis (parasitic disease of brain caused by the protozoan toxoplasma gondii)
Febrile neutropenia (fever with reduced white blood cells)
Gastrointestinal viral infection (virus infection of gastrointestinal tract)
Headache (pain in head)
Infection reactivation
Nausea (feeling of having an urge to vomit)

20-29:

Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Diarrhoea
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Hepatic necrosis (large portions of liver die off due to severe liver disease)
Hepatic pain (pain in liver)
Hepatitis fulminant (life-threatening condition defined by significantly impaired liver function)
Hepatomegaly (abnormal enlargement of the liver)
Myelosuppression (a decrease in the production of blood cells)
Neutropenia (an abnormally low number of neutrophils)
Oedema (fluid collection in tissue)

30-39:

Bone marrow failure
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)

40-49:

Bone marrow failure
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Diffuse large b-cell lymphoma stage iii (cancer of b cells, a type of white blood cell-stage iii)
Malignant neoplasm progression (cancer tumour came back)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pyrexia (fever)
Blood pressure decreased
Gait disturbance
Headache (pain in head)
Hyporeflexia (a condition of below normal or absent reflexes)

50-59:

Febrile neutropenia (fever with reduced white blood cells)
Thrombocytopenia (decrease of platelets in blood)
White blood cell count decreased
Basophil count decreased
Blood lactate dehydrogenase increased
Cd4 lymphocytes decreased
Cd4/cd8 ratio decreased
Eosinophil count decreased
Haematocrit decreased
Haemoglobin decreased

60+:

Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Febrile neutropenia (fever with reduced white blood cells)
Geotrichum infection (fungal infection by geotrichum)
Hypotension (abnormally low blood pressure)
Left ventricular dysfunction
Mucosal inflammation (infection of mucous membrane)
Nausea (feeling of having an urge to vomit)
Neoplasm progression (growth of tumour)
Pleural effusion (water on the lungs)
Septic shock (shock due to blood infection)

What are the existing conditions these people have? *

Bone Marrow Conditioning Regimen: 30 people, 42.25%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 14 people, 19.72%
Aplastic Anemia: 10 people, 14.08%
Febrile Neutropenia (fever with reduced white blood cells): 9 people, 12.68%
Constipation: 8 people, 11.27%
Sepsis (a severe blood infection that can lead to organ failure and death): 5 people, 7.04%
Pain: 5 people, 7.04%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 5 people, 7.04%
Nausea (feeling of having an urge to vomit): 5 people, 7.04%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 5 people, 7.04%

* Approximation only. Some reports may have incomplete information.

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