Clozaril and Foetal exposure during pregnancy - a phase IV clinical study of FDA data

Summary:

Foetal exposure during pregnancy is reported as a side effect among people who take Clozaril (clozapine), especially for people who are 0-1 old, have been taking the drug for 10+ years also take Sertraline, and have Depression.

The phase IV clinical study analyzes which people have Foetal exposure during pregnancy when taking Clozaril. It is created by eHealthMe based on reports of 64,938 people who have side effects when taking Clozaril from the FDA, and is updated regularly.

What is Clozaril?

Clozaril has active ingredients of clozapine. It is often used in schizophrenia. eHealthMe is studying from 65,127 Clozaril users. Check the latest studies of Clozaril.

What is Foetal exposure during pregnancy?

Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect) is found to be associated with 1,077 drugs and 1,129 conditions by eHealthMe. Check the latest studies of Foetal exposure during pregnancy.

On Jul, 11, 2026

64,938 people reported to have side effects when taking Clozaril.
Among them, 58 people (0.09%) have Foetal exposure during pregnancy.

Could Clozaril cause Foetal exposure during pregnancy?

Among these 58 people:

How long have people been on Clozaril when they have Foetal exposure during pregnancy? *

What is the age of people who have Foetal exposure during pregnancy when taking Clozaril? *

What are other drugs people take besides Clozaril? *

What are other side effects people have besides Foetal exposure during pregnancy? *

Premature Baby: 28 people, 48.28%
Drug Withdrawal Syndrome Neonatal (prenatal nas is caused by discontinuation of drugs taken by the pregnant mother): 4 people, 6.90%
Renal Impairment (severely reduced kidney function): 3 people, 5.17%
Dyspnea (difficult or laboured breathing): 3 people, 5.17%
Death: 3 people, 5.17%
Heart Rate Decreased: 3 people, 5.17%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 3.45%
Cardiac Disorder: 2 people, 3.45%
Haemoglobin Decreased: 2 people, 3.45%
Female Genital Tract Fistula (passage in genital tract of female): 2 people, 3.45%

What are the existing conditions these people have? *

Depression: 8 people, 13.79%
Stress And Anxiety: 3 people, 5.17%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 3.45%
Bipolar Disorder (mood disorder): 2 people, 3.45%
Weight Loss: 1 person, 1.72%
Salivary Hypersecretion (excess saliva secretion): 1 person, 1.72%
Psychotic Disorder: 1 person, 1.72%
High Blood Pressure: 1 person, 1.72%
Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 1 person, 1.72%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 1.72%

* Approximation only. Some reports may have incomplete information.

Do you take Clozaril and have Foetal exposure during pregnancy?

- Check whether Foetal exposure during pregnancy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Clozaril:

Clozaril (65,127 reports)

Browse all side effects of Clozaril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Foetal exposure during pregnancy:

Foetal exposure during pregnancy (1,077 drugs)

Browse all the conditions that are associated with Foetal exposure during pregnancy:

Foetal exposure during pregnancy (1,129 conditions)

Related publications that referenced our studies

Grover S, Sahoo S, "Clozapine induced akathisia: A case report and review of the evidence", Indian journal of pharmacology, 2015 Jan .
Yaylaci S, Yilmaz EU, Guclu E, Kumsar NA, Tamer A, Karabay O, "Clozapine-Induced Febrile Neutropenia and Cellulitis", Turkish journal of emergency medicine, 2014 Mar .
Grover S, Sahoo S, "Clozapine induced akathisia: A case report and review of the evidence", Indian journal of pharmacology, 2015 Jan .
Yaylaci S, Yilmaz EU, Guclu E, Kumsar NA, Tamer A, Karabay O, "Clozapine-Induced Febrile Neutropenia and Cellulitis", Turkish journal of emergency medicine, 2014 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on clozapine (the active ingredients of Clozaril) and Clozaril (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.