Sitagliptin phosphate and Vicodin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sitagliptin phosphate (sitagliptin phosphate) and Vicodin (acetaminophen; hydrocodone bitartrate). Common drug interactions include memory impairment among females and pancreatitis acute among males.

The phase IV clinical study analyzes what interactions people have when they take Sitagliptin phosphate and Vicodin. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Sitagliptin phosphate?

Sitagliptin phosphate has active ingredients of sitagliptin phosphate. eHealthMe is studying from 3,787 Sitagliptin phosphate users. Check the latest studies of Sitagliptin phosphate.

What is Vicodin?

Vicodin has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 63,357 Vicodin users. Check the latest studies of Vicodin.



On Jul, 11, 2026

11 people who take Sitagliptin phosphate and Vicodin together, and have interactions are studied.

Sitagliptin phosphate and Vicodin drug interactions.

What are the common drug interactions of Sitagliptin Phosphate and Vicodin, by gender? *:

female:

  1. Memory impairment
  2. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  3. Diarrhoea
  4. Dysarthria (speech disorder)
  5. Eye swelling
  6. Gait disturbance
  7. Hallucination (an experience involving the perception of something not present)
  8. Herpes zoster
  9. Laceration (tearing of soft body tissue)
  10. Pain in extremity

male:

  1. Pancreatitis acute (sudden inflammation of pancreas)

What are the common drug interactions of Sitagliptin Phosphate and Vicodin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  2. Diarrhoea
  3. Pain in extremity
  4. Tremor (trembling or shaking movements in one or more parts of your body)

50-59:

  1. Cardiac disorder
  2. Memory impairment
  3. Eye swelling
  4. Vision blurred

60+:

  1. Electrocardiogram qt prolonged
  2. Thrombosis (formation of a blood clot inside a blood vessel)
  3. Herpes zoster
  4. Laceration (tearing of soft body tissue)
  5. Memory impairment
  6. Pancreatitis acute (sudden inflammation of pancreas)
  7. Speech disorder
  8. Vomiting
  9. Activities of daily living impaired
  10. Balance disorder

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 4 people, 36.36%
  2. Stress And Anxiety: 3 people, 27.27%
  3. Depression: 3 people, 27.27%
  4. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2 people, 18.18%
  5. Migraine (headache): 2 people, 18.18%
  6. Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 2 people, 18.18%
  7. Chest Pain: 2 people, 18.18%
  8. Asthma: 2 people, 18.18%
  9. Arterial Disorder: 2 people, 18.18%
  10. Type 2 Diabetes: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Sitagliptin phosphate and Vicodin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Sitagliptin phosphate and Vicodin:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Sitagliptin phosphate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Vicodin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sitagliptin phosphate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vicodin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on sitagliptin phosphate and acetaminophen; hydrocodone bitartrate (the active ingredients of Sitagliptin phosphate and Vicodin, respectively), and Sitagliptin phosphate and Vicodin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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