Maxzide and Flector drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Maxzide (hydrochlorothiazide; triamterene) and Flector (diclofenac epolamine). Common drug interactions include dysarthria among females and body height decreased among males.
The phase IV clinical study analyzes what interactions people have when they take Maxzide and Flector. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.
What is Maxzide?
Maxzide has active ingredients of hydrochlorothiazide; triamterene. It is often used in high blood pressure. eHealthMe is studying from 9,152 Maxzide users. Check the latest studies of Maxzide.
What is Flector?
Flector has active ingredients of diclofenac epolamine. It is often used in pain. eHealthMe is studying from 5,112 Flector users. Check the latest studies of Flector.
16 people who take Maxzide and Flector together, and have interactions are studied.

What are the common drug interactions of Maxzide and Flector, by gender? *:
female:
- Dysarthria (speech disorder)
- Facial paralysis (loss of function of face muscle)
- Hemiparesis (weakness on one side of the body)
- Rash
- Arthralgia (joint pain)
- Dizziness
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
- Migraine (headache)
- Mobility decreased (ability to move is reduced)
male:
- Body height decreased
- Bone marrow failure
- Weight increased
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Fatigue (feeling of tiredness)
- Immunosuppression
- Infection
- Oedema peripheral (superficial swelling)
- Pericarditis (inflammation of the pericardium)
- Pleurisy (inflammation of the pleurae, which causes pain when breathing)
What are the common drug interactions of Maxzide and Flector, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Dysarthria (speech disorder)
- Facial paralysis (loss of function of face muscle)
- Hemiparesis (weakness on one side of the body)
- Migraine (headache)
- Poor quality sleep
- Hemiplegic migraine (migraine attacks occurring in two or more people in the same family who experience weakness on one side of body)
50-59:
n/a
60+:
- Rash
- Arthralgia (joint pain)
- Fall
- Fatigue (feeling of tiredness)
- Heart rate increased
- Immunosuppression
- Infection
- Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
- Oropharyngeal pain
- Pericarditis (inflammation of the pericardium)
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 50.00%
- High Blood Cholesterol: 5 people, 31.25%
- Joint Pain: 3 people, 18.75%
- Myositis (inflammation of the muscles): 2 people, 12.50%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 12.50%
- Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 12.50%
- Blood Pressure Abnormal: 2 people, 12.50%
- Blood Potassium Abnormal: 2 people, 12.50%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 12.50%
- Staphylococcal Infection (an infection with staphylococcus bacteria): 1 person, 6.25%
* Approximation only. Some reports may have incomplete information.
Do you take Maxzide and Flector?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Maxzide and Flector:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Maxzide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Flector:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Maxzide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Flector and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on hydrochlorothiazide; triamterene and diclofenac epolamine (the active ingredients of Maxzide and Flector, respectively), and Maxzide and Flector (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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