Fluoride and Alendronate sodium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fluoride (fluoride) and Alendronate sodium (alendronate sodium). Common drug interactions include headache among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Fluoride and Alendronate sodium. It is created by eHealthMe based on reports of 56 people who take the same drugs from the FDA, and is updated regularly.

What is Fluoride?

Fluoride has active ingredients of fluoride. eHealthMe is studying from 2,301 Fluoride users. Check the latest studies of Fluoride.

What is Alendronate sodium?

Alendronate sodium has active ingredients of alendronate sodium. It is often used in osteoporosis. eHealthMe is studying from 43,608 Alendronate sodium users. Check the latest studies of Alendronate sodium.

On Jul, 15, 2026

56 people who take Fluoride and Alendronate sodium together, and have interactions are studied.

Fluoride and Alendronate sodium drug interactions.

What are the common drug interactions of Fluoride and Alendronate Sodium, by gender? *:

female:

Headache (pain in head)
Abdominal discomfort
Infusion related reaction
Fibromyalgia (a long-term condition which causes pain all over the body)
Helicobacter infection (helicobacter pylori (h. pylori) infects stomach)
Arthralgia (joint pain)
Blood cholesterol increased
General physical health deterioration (weak health status)
Hepatic enzyme increased
Dizziness

male:

Asthenia (weakness)
Cataract (clouding of the lens inside the eye)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Post procedural complication
Arthralgia (joint pain)
Balance disorder
Knee arthroplasty

What are the common drug interactions of Fluoride and Alendronate Sodium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Pericarditis (inflammation of the pericardium)
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Urticaria (rash of round, red welts on the skin that itch intensely)
Weight increased
Folliculitis (infection of hair root)
Irritable bowel syndrome
Anti-cyclic citrullinated peptide antibody positive
Arthropathy

50-59:

Mobility decreased (ability to move is reduced)
Alopecia (absence of hair from areas of the body)
Anxiety
Asthma
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Blood cholesterol increased
Decreased appetite
Discomfort
Drug ineffective
Drug intolerance (drug sensitivity)

60+:

Osteonecrosis (death of bone)
Osteonecrosis of jaw (death of bone of jaw)
Encephalopathy (functioning of the brain is affected by some agent or condition)
Failure to thrive (inadequate weight gain and physical growth in children)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hepatic failure (liver failure)
Hyperkalaemia (damage to or disease of the kidney)
Increased upper airway secretion
Post procedural haemorrhage (post procedural bleeding)
Skin haemorrhage (bleeding into skin)

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 23 people, 41.07%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 18 people, 32.14%
Indigestion: 17 people, 30.36%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 17 people, 30.36%
Psoriasis (immune-mediated disease that affects the skin): 14 people, 25.00%
Fibromyalgia (a long-term condition which causes pain all over the body): 14 people, 25.00%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 13 people, 23.21%
Headache (pain in head): 13 people, 23.21%
Pain: 4 people, 7.14%
High Blood Pressure: 4 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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