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Fluoride and Vitamin e drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fluoride (fluoride) and Vitamin e (tocopherols and tocotrienols). Common drug interactions include cough among females and mucosal inflammation among males.

The phase IV clinical study analyzes what interactions people have when they take Fluoride and Vitamin e. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Fluoride?

Fluoride has active ingredients of fluoride. eHealthMe is studying from 2,301 Fluoride users. Check the latest studies of Fluoride.

What is Vitamin e?

Vitamin e has active ingredients of tocopherols and tocotrienols. It is often used in vitamin supplementation. eHealthMe is studying from 42,279 Vitamin e users. Check the latest studies of Vitamin e.



On Jul, 23, 2026

30 people who take Fluoride and Vitamin e together, and have interactions are studied.

Fluoride and Vitamin e drug interactions.

What are the common drug interactions of Fluoride and Vitamin E, by gender? *:

female:

  1. Cough
  2. Jaw disorder (jaw disease)
  3. Depression
  4. Fall
  5. Infection
  6. Pneumonia
  7. Gait disturbance
  8. Ill-defined disorder
  9. Asthenia (weakness)
  10. Balance disorder

male:

  1. Mucosal inflammation (infection of mucous membrane)
  2. Diarrhoea
  3. Bone marrow disorder
  4. Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
  5. Decreased appetite
  6. Drug hypersensitivity
  7. Feeding disorder (when children refuse to eat certain food groups)
  8. Flatulence (flatus expelled through the anus)
  9. Forced expiratory volume decreased (decreased lung expired air volume)
  10. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

What are the common drug interactions of Fluoride and Vitamin E, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Blood 25-hydroxycholecalciferol decreased
  2. Blood chloride increased
  3. Blood iron decreased
  4. Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
  5. Pulmonary function test decreased
  6. Staphylococcal infection (an infection with staphylococcus bacteria)
  7. Vascular access complication

10-19:

  1. Forced expiratory volume decreased (decreased lung expired air volume)

20-29:

n/a

30-39:

  1. Blood bilirubin increased
  2. Feeding disorder (when children refuse to eat certain food groups)
  3. Mucosal inflammation (infection of mucous membrane)

40-49:

  1. Mucosal inflammation (infection of mucous membrane)
  2. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  3. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  4. Pericarditis (inflammation of the pericardium)

50-59:

  1. Diarrhoea
  2. Nausea (feeling of having an urge to vomit)
  3. Anaemia (lack of blood)
  4. Anal abscess
  5. Asthenia (weakness)
  6. Bone marrow disorder
  7. Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
  8. Decreased appetite
  9. Dizziness
  10. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

60+:

  1. Cough
  2. Jaw disorder (jaw disease)
  3. Cystitis (inflammation of the wall of the bladder)
  4. Limb discomfort (discomfort in leg)
  5. Mobility decreased (ability to move is reduced)
  6. Muscular weakness (muscle weakness)
  7. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  8. Tinea pedis (a contagious skin infection caused by the ringworm fungus)
  9. Fatigue (feeling of tiredness)
  10. Secondary progressive multiple sclerosis (a stage of ms which comes after relapsing remitting ms in many cases)

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 9 people, 30.00%
  2. Gait Disturbance: 7 people, 23.33%
  3. Cystic Fibrosis (disease of the secretary glands): 5 people, 16.67%
  4. Pain: 3 people, 10.00%
  5. Hypersensitivity: 3 people, 10.00%
  6. Dyspnea (difficult or laboured breathing): 3 people, 10.00%
  7. Multiple Myeloma (cancer of the plasma cells): 2 people, 6.67%
  8. Joint Pain: 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Fluoride and Vitamin e?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Fluoride and Vitamin e:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Fluoride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Vitamin e:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Fluoride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vitamin e and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on fluoride and tocopherols and tocotrienols (the active ingredients of Fluoride and Vitamin e, respectively), and Fluoride and Vitamin e (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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