Fluoxetine and Zinacef drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fluoxetine (fluoxetine hydrochloride) and Zinacef (cefuroxime sodium). Common drug interactions include ear pain among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Fluoxetine and Zinacef. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Fluoxetine?

Fluoxetine has active ingredients of fluoxetine hydrochloride. It is often used in depression. eHealthMe is studying from 98,823 Fluoxetine users. Check the latest studies of Fluoxetine.

What is Zinacef?

Zinacef has active ingredients of cefuroxime sodium. eHealthMe is studying from 1,802 Zinacef users. Check the latest studies of Zinacef.

On Jul, 27, 2026

24 people who take Fluoxetine and Zinacef together, and have interactions are studied.

Fluoxetine and Zinacef drug interactions.

What are the common drug interactions of Fluoxetine and Zinacef, by gender? *:

female:

Ear pain
Escherichia infection (bacterial infection by escherichia coli)
Facial bones fracture (bone fracture of face)
Fall
Gingival bleeding (bleeding gums)
Gingival swelling (gums swelling)
Hip fracture
Injury
Intervertebral disc degeneration (spinal disc degeneration)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)

male:

Nausea (feeling of having an urge to vomit)
Abdominal pain
Agitation (state of anxiety or nervous excitement)
Ascites (accumulation of fluid in the abdominal cavity)
Blood pressure increased
Confusional state
Cytomegalovirus infection
Emotional distress
Face oedema (swelling of face)
Haematemesis (vomiting of blood)

What are the common drug interactions of Fluoxetine and Zinacef, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Hepatic necrosis (large portions of liver die off due to severe liver disease)
Splenomegaly (enlargement of spleen)
Abdominal pain
Ascites (accumulation of fluid in the abdominal cavity)
Blood pressure increased
Cytomegalovirus infection
Face oedema (swelling of face)
Hepatic failure (liver failure)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Insomnia (sleeplessness)

40-49:

Aortic valve replacement
Asthenia (weakness)
Blood culture positive
Confusional state
Dermatitis allergic (inflammation of the skin due allergic reaction)
Difficulty in walking
Emotional distress
Eosinophil count increased
Exanthem (rashes on skin by viral infection)
Hallucination (an experience involving the perception of something not present)

50-59:

Weight decreased
Abdominal pain
Confusional state
Decreased appetite
Emotional distress
Fatigue (feeling of tiredness)
Abnormal dreams
Burning sensation
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)

60+:

Blood lactate dehydrogenase increased
Anaemia (lack of blood)
Ear pain
Escherichia infection (bacterial infection by escherichia coli)
Facial bones fracture (bone fracture of face)
Fall
Gingival bleeding (bleeding gums)
Gingival swelling (gums swelling)
Hip fracture
Injury

* Approximation only. Some reports may have incomplete information.

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