Fluticasone propionate and Arthrotec drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Fluticasone propionate (fluticasone propionate) and Arthrotec (diclofenac sodium; misoprostol). Common drug interactions include hypertension among females and mitral valve incompetence among males.

The phase IV clinical study analyzes what interactions people have when they take Fluticasone propionate and Arthrotec. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.

What is Fluticasone propionate?

Fluticasone propionate has active ingredients of fluticasone propionate. It is often used in allergies. eHealthMe is studying from 35,174 Fluticasone propionate users. Check the latest studies of Fluticasone propionate.

What is Arthrotec?

Arthrotec has active ingredients of diclofenac sodium; misoprostol. It is often used in arthritis. eHealthMe is studying from 11,986 Arthrotec users. Check the latest studies of Arthrotec.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 15, 2026

45 people who take Fluticasone propionate and Arthrotec together, and have interactions are studied.

Fluticasone propionate and Arthrotec drug interactions.

What are the common drug interactions of Fluticasone Propionate and Arthrotec, by gender? *:

female:

Hypertension (high blood pressure)
Impaired healing
Breast cancer
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Neuropathy peripheral (surface nerve damage)
Purpura senile (skin condition in which areas of the skin develop a purplish or reddish-brown appearance due to bleeding of small blood vessels underneath)
Renal failure (kidney dysfunction)
Weight decreased
Adverse event
Allergy to arthropod bite

male:

Mitral valve incompetence (inefficient heart valve)
Weight increased
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Anger
Asthenia (weakness)
Chest pain
Coronary artery atherosclerosis (life-threatening blockages in the arteries of your heart)
Fall
Gait disturbance
Gastrointestinal disorder (functional problems of gastrointestinal tract)

What are the common drug interactions of Fluticasone Propionate and Arthrotec, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
Cholecystitis chronic (long lasting infection of gallbladder)
Gallbladder disorder

30-39:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dizziness
Glaucoma (increased fluid pressure in the eye with vision loss)
Neuropathy peripheral (surface nerve damage)
Purpura senile (skin condition in which areas of the skin develop a purplish or reddish-brown appearance due to bleeding of small blood vessels underneath)
Renal failure (kidney dysfunction)
Resorption bone increased
Tarsal tunnel syndrome (a condition that is caused by compression of the tibial nerve or its associated branches as the nerve)

40-49:

Renal cyst (kidney cyst)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Rotator cuff repair
Sacroiliitis (an inflammation of the sacroiliac joint)
Spinal osteoarthritis (joint cartilage loss in spine)
Staphylococcal infection (an infection with staphylococcus bacteria)
Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
Synovitis (inflammation of the synovial membrane)
Temporomandibular joint syndrome (pain at the temporomandibular joint due to various causes of increased muscle tension and spasm. it is believed that syndrome is a physical manifestation of psychological stress)
Tendonitis (a condition that causes pain and swelling of tendons)

50-59:

n/a

60+:

Breast cancer
Diarrhoea
Contusion (a type of hematoma of tissue in which capillaries)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Cough
Dysarthria (speech disorder)
Dyspnoea (difficult or laboured respiration)
Facial pain
Fatigue (feeling of tiredness)
Gait disturbance

What are the existing conditions these people have? *

Depression: 7 people, 15.56%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 13.33%
Muscle Spasms (muscle contraction): 5 people, 11.11%
High Blood Pressure: 5 people, 11.11%
Stress And Anxiety: 4 people, 8.89%
Multiple Allergies (allergy to multiple agents): 4 people, 8.89%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 4 people, 8.89%
Sleep Disorder: 3 people, 6.67%
Premenstrual Syndrome: 3 people, 6.67%
Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 3 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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