Fluvastatin and Digoxin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Fluvastatin (fluvastatin) and Digoxin (digoxin). Common drug interactions include nephrogenic anaemia among females and dyspnoea among males.
The phase IV clinical study analyzes what interactions people have when they take Fluvastatin and Digoxin. It is created by eHealthMe based on reports of 52 people who take the same drugs from the FDA, and is updated regularly.
What is Fluvastatin?
Fluvastatin has active ingredients of fluvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 3,999 Fluvastatin users. Check the latest studies of Fluvastatin.
What is Digoxin?
Digoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 93,740 Digoxin users. Check the latest studies of Digoxin.
52 people who take Fluvastatin and Digoxin together, and have interactions are studied.

What are the common drug interactions of Fluvastatin and Digoxin, by gender? *:
female:
- Nephrogenic anaemia (anaemia due to kidney disease)
- Pneumonia
- Renal failure (kidney dysfunction)
- Renal tubular necrosis (death of kidney tubules)
- Abdominal pain
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Asthenia (weakness)
- Blood creatinine increased
- Blood glucose increased
male:
- Dyspnoea (difficult or laboured respiration)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Haemorrhage (bleeding)
- Hyperkalaemia (damage to or disease of the kidney)
- Pulmonary oedema (fluid accumulation in the lungs)
- Cardiac failure
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Cough
- Hypotension (abnormally low blood pressure)
- Sputum discoloured
What are the common drug interactions of Fluvastatin and Digoxin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- International normalised ratio increased
- Vaginal haemorrhage (vaginal bleeding)
40-49:
- Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
- Cardiac failure
- Cardiac failure congestive
- Cardiac output decreased
- Chest pain
- Congestive cardiomyopathy (weakening of heart muscle)
- Diabetes mellitus inadequate control
- Enthesopathy (disorder of entheses (bone attachments))
- Erectile dysfunction
- Fall
50-59:
- Cardiac arrest
- Viral diarrhoea
60+:
- Dyspnoea (difficult or laboured respiration)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Haemoglobin decreased
- Haemorrhage (bleeding)
- Pneumonia
- Pulmonary oedema (fluid accumulation in the lungs)
- Cough
- Hypotension (abnormally low blood pressure)
- Renal failure (kidney dysfunction)
- Acute myocardial infarction (acute heart attack)
What are the existing conditions these people have? *
- Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 6 people, 11.54%
- Pulmonary Embolism (blockage of the main artery of the lung): 6 people, 11.54%
- Hyperlipidaemia (presence of excess lipids in the blood): 6 people, 11.54%
- Depression: 5 people, 9.62%
- High Blood Pressure: 4 people, 7.69%
- Cough: 4 people, 7.69%
- Cardiac Failure Congestive: 4 people, 7.69%
- Vertebrobasilar Circulatory Disorders (several disorders involving the basilar and vertebral arteries which disrupts blood flow to the brain stem and cerebellum clinical episodic dizziness, double vision, weakness, and dysarthria): 3 people, 5.77%
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 3 people, 5.77%
- Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 3 people, 5.77%
* Approximation only. Some reports may have incomplete information.
Do you take Fluvastatin and Digoxin?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Fluvastatin (3,999 reports)
- Digoxin (93,740 reports)
Browse all drug interactions of Fluvastatin and Digoxin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Fluvastatin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Digoxin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Fluvastatin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Digoxin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Guru SR, Suresh A, Padmanabhan S, Reddy A, "A Rare Case of Digoxin Associated Gingival Overgrowth", Journal of clinical and diagnostic research: JCDR, 2017 Jan .
- Liao KF, Huang PT, Lin CC, Lin CL, Lai SW, "Fluvastatin use and risk of acute pancreatitis: a population-based case-control study in Taiwan", Biomedicine, 2017 Jan .
- Lai SW, Lin CL, Liao KF, "Digoxin use may increase the relative risk of acute pancreatitis: a population-based case–control study in Taiwan", International journal of cardiology, 2015 Feb .
- Liao, K. F., Huang, P. T., Lin, C. C., Lin, C. L., & Lai, S. W., "Fluvastatin use and risk of acute pancreatitis: a population-based case-control study in Taiwan", Biomedicine, 2014 Jan .
- Guru SR, Suresh A, Padmanabhan S, Reddy A, "A Rare Case of Digoxin Associated Gingival Overgrowth", Journal of clinical and diagnostic research: JCDR, 2017 Jan .
- Liao KF, Huang PT, Lin CC, Lin CL, Lai SW, "Fluvastatin use and risk of acute pancreatitis: a population-based case-control study in Taiwan", Biomedicine, 2017 Jan .
- Lai SW, Lin CL, Liao KF, "Digoxin use may increase the relative risk of acute pancreatitis: a population-based case–control study in Taiwan", International journal of cardiology, 2015 Feb .
- Liao, K. F., Huang, P. T., Lin, C. C., Lin, C. L., & Lai, S. W., "Fluvastatin use and risk of acute pancreatitis: a population-based case-control study in Taiwan", Biomedicine, 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on fluvastatin and digoxin (the active ingredients of Fluvastatin and Digoxin, respectively), and Fluvastatin and Digoxin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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