Focalin and Voltaren drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Focalin (dexmethylphenidate hydrochloride) and Voltaren (diclofenac sodium). Common drug interactions include hypersensitivity among females and cellulitis among males.

The phase IV clinical study analyzes what interactions people have when they take Focalin and Voltaren. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Focalin?

Focalin has active ingredients of dexmethylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 4,781 Focalin users. Check the latest studies of Focalin.

What is Voltaren?

Voltaren has active ingredients of diclofenac sodium. It is often used in arthritis. eHealthMe is studying from 82,346 Voltaren users. Check the latest studies of Voltaren.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

21 people who take Focalin and Voltaren together, and have interactions are studied.

What are the common drug interactions of Focalin and Voltaren, by gender? *:

female:

Hypersensitivity
Pruritus generalised (generalized itching)
Urticaria (rash of round, red welts on the skin that itch intensely)
Abdominal abscess (collection of pus in abdomen)
Appendicitis perforated (perforated appendicitis is a condition in which an inflamed appendix bursts)
Nausea (feeling of having an urge to vomit)
Vomiting
Ligament rupture (tear in ligament)
Malaise (a feeling of general discomfort or uneasiness)
Sinusitis (inflammation of sinus)

male:

Cellulitis (infection under the skin)
Cough
Fibromyalgia (a long-term condition which causes pain all over the body)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Nasopharyngitis (inflammation of the nasopharynx)
Oropharyngeal pain
Weight decreased

What are the common drug interactions of Focalin and Voltaren, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abnormal sleep-related event
Sinusitis (inflammation of sinus)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

40-49:

Dysphagia (a condition in which swallowing is difficult or painful)
Dysphonia (speech disorder attributable to a disorder of phonation)
Dyspnoea (difficult or laboured respiration)
Hypersensitivity
Pruritus generalised (generalized itching)
Urticaria (rash of round, red welts on the skin that itch intensely)
Abdominal abscess (collection of pus in abdomen)
Appendicitis perforated (perforated appendicitis is a condition in which an inflamed appendix bursts)
Nausea (feeling of having an urge to vomit)
Vomiting

50-59:

Weight decreased
Cellulitis (infection under the skin)
Cough
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Nasopharyngitis (inflammation of the nasopharynx)
Oropharyngeal pain

60+:

Colon cancer
Fatigue (feeling of tiredness)
Ligament rupture (tear in ligament)
Rectal cancer stage ii (rectal cancer has spread to other organs near the colon or rectum. it has not reached lymph nodes)
Therapeutic response unexpected

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 38.10%
Depression: 6 people, 28.57%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 23.81%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 23.81%
Back Pain: 5 people, 23.81%
Metastases To Bone (cancer spreads to bone): 3 people, 14.29%
Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 14.29%
Breast Cancer: 3 people, 14.29%
Breast Cancer Metastatic: 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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