Saxenda and Malaise - a phase IV clinical study of FDA data

Summary:

Malaise is reported as a side effect among people who take Saxenda (liraglutide recombinant), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Xeljanz, and have Weight decreased.

The phase IV clinical study analyzes which people have Malaise when taking Saxenda. It is created by eHealthMe based on reports of 6,333 people who have side effects when taking Saxenda from the FDA, and is updated regularly.

What is Saxenda?

Saxenda has active ingredients of liraglutide recombinant. It is often used in weight loss. eHealthMe is studying from 6,735 Saxenda users. Check the latest studies of Saxenda.

What is Malaise?

Malaise (a feeling of general discomfort or uneasiness) is found to be associated with 3,488 drugs and 5,129 conditions by eHealthMe. Check the latest studies of Malaise.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

6,333 people reported to have side effects when taking Saxenda.
Among them, 152 people (2.4%) have Malaise.

Among these 152 people:

* Approximation only. Some reports may have incomplete information.

Do you take Saxenda and have Malaise?

- Check whether Malaise is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Saxenda:

Saxenda (6,735 reports)

Malaise treatments and more:

Malaise (529,933 reports)

How severe was Malaise and when was it recovered:

Malaise in Saxenda

Expand to all the drugs that have ingredients of liraglutide recombinant:

Malaise and drugs with ingredients of liraglutide recombinant (292 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Saxenda:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Malaise:

Malaise (3,488 drugs)

Browse all the conditions that are associated with Malaise:

Malaise (5,129 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on liraglutide recombinant (the active ingredients of Saxenda) and Saxenda (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.