Niacin and Zeaxanthin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Niacin (niacin) and Zeaxanthin (lutein). Common drug interactions include conjunctivitis among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Niacin and Zeaxanthin. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Niacin?

Niacin has active ingredients of niacin. It is often used in high blood cholesterol. eHealthMe is studying from 9,009 Niacin users. Check the latest studies of Niacin.

What is Zeaxanthin?

Zeaxanthin has active ingredients of lutein. It is often used in macular degeneration. eHealthMe is studying from 1,687 Zeaxanthin users. Check the latest studies of Zeaxanthin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 31, 2026

16 people who take Niacin and Zeaxanthin together, and have interactions are studied.

Niacin and Zeaxanthin drug interactions.

What are the common drug interactions of Niacin and Zeaxanthin, by gender? *:

female:

  1. Conjunctivitis (pink eye)
  2. Diarrhoea
  3. Fall
  4. Accident at home
  5. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  6. Erythema (redness of the skin)
  7. Fatigue (feeling of tiredness)
  8. Foot fracture
  9. Hallucination (an experience involving the perception of something not present)
  10. Immunoglobulins decreased

male:

  1. Pain
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
  4. Drug hypersensitivity
  5. Erythema (redness of the skin)
  6. Eye pruritus (eye itching)
  7. Gastrointestinal viral infection (virus infection of gastrointestinal tract)
  8. Hypoaesthesia (reduced sense of touch or sensation)
  9. Oedema peripheral (superficial swelling)
  10. Oral herpes (viral infection of mouth)

What are the common drug interactions of Niacin and Zeaxanthin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Conjunctivitis (pink eye)
  2. Diarrhoea
  3. Immunoglobulins decreased
  4. Oropharyngeal pain
  5. Osteochondrosis (a family of orthopaedic diseases of the joint that occur in children and adolescents)
  6. Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
  7. Psychotic disorder
  8. Rash
  9. Stress
  10. Abdominal distension

What are the existing conditions these people have? *

  1. Primary Immunodeficiency Syndrome: 2 people, 12.50%
  2. Multiple Myeloma (cancer of the plasma cells): 2 people, 12.50%
  3. Immunodeficiency Common Variable: 2 people, 12.50%
  4. Hiv Infection: 2 people, 12.50%
  5. Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 2 people, 12.50%
  6. Psoriasis (immune-mediated disease that affects the skin): 1 person, 6.25%
  7. Pain In Extremity: 1 person, 6.25%
  8. Pain: 1 person, 6.25%
  9. Osteoporosis (bones weak and more likely to break): 1 person, 6.25%
  10. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Niacin and Zeaxanthin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Niacin and Zeaxanthin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Niacin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Zeaxanthin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Niacin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zeaxanthin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on niacin and lutein (the active ingredients of Niacin and Zeaxanthin, respectively), and Niacin and Zeaxanthin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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