Folic acid and Zinacef drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Folic acid (folic acid) and Zinacef (cefuroxime sodium). Common drug interactions include alanine aminotransferase increased among females and injury among males.

The phase IV clinical study analyzes what interactions people have when they take Folic acid and Zinacef. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Folic acid?

Folic acid has active ingredients of folic acid. It is often used in rheumatoid arthritis. eHealthMe is studying from 165,025 Folic acid users. Check the latest studies of Folic acid.

What is Zinacef?

Zinacef has active ingredients of cefuroxime sodium. eHealthMe is studying from 1,802 Zinacef users. Check the latest studies of Zinacef.



On Jul, 21, 2026

17 people who take Folic acid and Zinacef together, and have interactions are studied.

Folic acid and Zinacef drug interactions.

What are the common drug interactions of Folic Acid and Zinacef, by gender? *:

female:

  1. Alanine aminotransferase increased
  2. Aspartate aminotransferase increased
  3. Blood alkaline phosphatase nos increased
  4. Blood bilirubin increased
  5. Blood pressure decreased
  6. Cough
  7. Fatigue (feeling of tiredness)
  8. Haemoglobin decreased
  9. Pneumonia
  10. Renal failure (kidney dysfunction)

male:

  1. Injury
  2. Pain
  3. Foetal distress syndrome (altered heart rate or rhythm and leading tocompromised blood flow or changes in blood chemistry of foetus)
  4. Hypoglycaemia neonatal (deficiency of glucose in the bloodstream in neonatal)
  5. Lower limb fracture
  6. Renal impairment (severely reduced kidney function)
  7. Spinal fracture (fracture in one of vertebrae)
  8. Stress
  9. Renal failure acute (rapid kidney dysfunction)
  10. Aortic valve stenosis (narrowing of the aortic valve)

What are the common drug interactions of Folic Acid and Zinacef, by age (0-1 to 60+)? *:

0-1:

  1. Foetal distress syndrome (altered heart rate or rhythm and leading tocompromised blood flow or changes in blood chemistry of foetus)
  2. Hypoglycaemia neonatal (deficiency of glucose in the bloodstream in neonatal)
  3. Developmental delay
  4. Placental insufficiency

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Chronic kidney disease
  2. Death
  3. Nephrogenic anaemia (anaemia due to kidney disease)
  4. Renal failure (kidney dysfunction)

50-59:

n/a

60+:

  1. Renal failure (kidney dysfunction)
  2. Injury
  3. Thrombocytopenia (decrease of platelets in blood)
  4. Renal failure acute (rapid kidney dysfunction)
  5. Alanine aminotransferase increased
  6. Aspartate aminotransferase increased
  7. Blood alkaline phosphatase nos increased
  8. Blood bilirubin increased
  9. Blood pressure decreased
  10. Cough

What are the existing conditions these people have? *

  1. Diabetes: 5 people, 29.41%
  2. Constipation: 3 people, 17.65%
  3. Anaemia (lack of blood): 3 people, 17.65%
  4. High Blood Cholesterol: 3 people, 17.65%
  5. High Blood Pressure: 3 people, 17.65%
  6. Enlarged Prostate: 2 people, 11.76%
  7. Temporal Arteritis (inflammation and damage to blood vessels that supply the head area): 2 people, 11.76%
  8. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 2 people, 11.76%
  9. Alcoholism (problems with alcohol): 2 people, 11.76%
  10. Nausea (feeling of having an urge to vomit): 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

Do you take Folic acid and Zinacef?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Folic acid and Zinacef:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Folic acid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Zinacef:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Folic acid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zinacef and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on folic acid and cefuroxime sodium (the active ingredients of Folic acid and Zinacef, respectively), and Folic acid and Zinacef (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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